Screenings and Diagnostic procedures

Answering your questions, and detecting or ruling out potential issues with your baby’s development is what the High-Risk Pregnancy Program at The Ohio State University Wexner Medical Center is all about. For nearly 30 years, we’ve offered expectant mothers the latest in personalized maternal and fetal screenings and diagnostic procedures. Together with you and your primary Ob/Gyn, along with the information we learn from testing, we develop an individualized treatment and delivery plan.

Our Patients

Women experiencing high-risk pregnancies, as well as to those with a routine pregnancy who wish to learn more about their baby’s development come to us for prenatal screenings and diagnostics. While the majority of our patients ultimately experience a smooth pregnancy, those with complications can meet with a specialist to discuss findings and develop a delivery and post-delivery care plan, if needed.

Because we work closely with your primary Ob/Gyn, we’ll send results immediately so that, together, we can determine your best plan. Your treatment plan may include fetal procedures, genetic evaluations, maternal therapies, in-hospital care or a special birthing plan.

Why Choose Ohio State?

Obstetricians and gynecologists throughout our region regularly refer their patients to Ohio State for maternal and fetal screenings because of our expertise in the field. Our team of experienced perinatologists, sonographers, genetic counselors and nurses provide expert, compassionate care that is co-managed with your Ob/Gyn.

As the only academic medical center in central Ohio, our physicians are actively involved in clinical research and have participated in the development and testing of many of the screen and diagnostic procedures we offer.

Our Services


This screening at 15 weeks involves extracting a small sample of amniotic fluid to identify or rule out chromosome abnormalities such as Down syndrome, birth defects such as spina bifida, or genetic conditions, such as cystic fibrosis.

Cervical Length Assessment

This examination uses transvaginal ultrasound to verify an incidental finding of a potentially short cervix that could lead to preterm delivery.

Cell-Free Fetal DNA Screening

This mother’s blood test, performed as early as 11 weeks, is used to learn more about baby’s Rh blood factor type or potential for chromosomal abnormalities, such as Down syndrome. Ohio State was one of the testing sites for this new screening process.

Chorionic Villus Sampling (CVS)

This diagnostic test at 10-12 weeks takes a sample of the developing placenta for laboratory analysis to identify or rule out chromosome abnormalities, such as Down syndrome, and certain genetic disorders, such as cystic fibrosis.

Fetal Blood Sampling (Cordocentesis)

This blood test takes a small amount of baby’s blood from the umbilical cord for laboratory analysis to help in diagnosing and monitoring a variety of conditions.

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Fetal Echocardiogram

This special ultrasound evaluates the structure and function of baby’s heart before birth to detect congenital heart defect.

Ultrascreen® Instant Risk Assessment/First Trimester Screening

This early-pregnancy assessment at 11-13 weeks combines blood tests with ultrasound to deliver a personalized risk assessment for Down syndrome, trisomy 18 and trisomy 13. Ohio State’s Maternal Fetal Medicine Division was the first in central Ohio to offer this faster, more accurate, non-invasive procedure.

Microarray Analysis Screening

Using a blood sample, this chromosome screen (usually ordered because of a potential genetic condition in the family) determines if there is an extra or missing gene that may affect baby’s growth or development.

Targeted Ultrasound

This state-of-the-art imaging technique evaluates baby’s size, position and development in diagnosing developmental abnormalities.

Doppler Study

This specialized ultrasound screening measures blood flow through a variety of blood vessels including the umbilical cord and brain.

Quad Screening

This blood test administered at 15-22 weeks screens for open neural tube defects (NTDs), such as spina bifida and anencephaly, abdominal wall defects, and chromosome changes, such as Down syndrome and trisomy 18.

Patient Success

Early diagnosis helped Courtney have a healthy baby

When Courtney's son Corbyn was diagnosed with complications during pregnancy she turned to Ohio State's Maternal Fetal Medicine experts.

Monitoring high-risk pregnancy provides peace of mind

​Dawn, age 37, of Dublin, Ohio, has learned how to deal with stress. Whether it's running her own baking business or juggling schedules for her family of four, she tackles life's hurdles one day at a time.

Tips from our Experts

Understanding Prenatal Screening and Testing Options at OSU Maternal Fetal Medicine

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