Assistant Professor, Department of Otolaryngology
BS: Peking University, Beijing China, biochemistry and molecular biology, 1997
MS: Institute of Genetics, Chinese Academy of Science, Beijing China, molecular genetics, 2000
PhD: University of Texas at Austin, neuroscience, 2006
Postdoctoral: University of North Carolina at Chapel Hill, neuroscience, 2012
- Age-related hearing loss
- Noise-induced hearing loss
- Mechanisms of synaptic transmission
- Function of the auditory neural network
- Brain aging
Current Research Support
Dates: 09/19/2017 – 08/31/2022
Name of Agency: National Institute on Deafness and Other Communication Disorders (NIDCD)
Award Number: R01 DC016037
Xie R*, Manis PB (2017). Synaptic transmission at the endbulb of Held deteriorates during age-related hearing loss. J Physiol 2017 Feb 1; 595(3):919-934. (*Correspondence)
Xie R* (2016). Transmission of auditory sensory information decreases in rate and temporal precision at the endbulb of Held synapse during age-related hearing loss. J Neurophysiol. 2016; 116(6):2695-2705. Special issue: Auditory System Plasticity. (*Correspondence)
Xie R and Manis PB (2014). GABAergic and glycinergic inhibitory synaptic transmission in the cochlear nucleus studied in VGAT channelrhodopsin-2 mice. Front Neural Circuits 2014 July 24;8:84.
Xie R and Manis PB (2013). Glycinergic synaptic transmission in the cochlear nucleus of mice with normal hearing and age-related hearing loss. J Neurophysiol. 2013 Oct; 110(8): 1848-1859.
Xie R and Manis PB (2013). Target-specific IPSC kinetics promote temporal processing in auditory parallel pathways. J Neuroscience. 2013 January 23; 33(4): 1598-1614. * Featured article in “This Week in The Journal”.
Rich AW, Xie R, and Manis PB (2010). Hearing loss alters quantal release at cochlear nucleus stellate cells. Laryngoscope. 2010 Oct; 120 (10): 2047-53.
Xie R, Gittelman JX, Li N, and Pollak GD (2008). Whole cell recordings of intrinsic properties and sound-evoked responses from the inferior colliculus. Neuroscience. 2008 June 12; 154(1):245-56.
Xie R, Gittelman JX, and Pollak GD (2007). Rethinking tuning: in vivo whole cell recordings of the inferior colliculus in awake bats. J Neuroscience. 2007 Aug 29; 27(35):9469-81.
Xie R, Meitzen J. and Pollak GD (2005). Differing roles of inhibition in hierarchical processing of species-specific calls in auditory brainstem nuclei. J Neurophysiol. 2005 Dec; 94(6):4019-37.
For latest publications, please check my bibliography URL:
Department of Neurosciences
University of Toledo
Assistant Professor, 2018 - Current
Department of Otolaryngology - Head and Neck Surgery
The Ohio State University College of Medicine, Columbus, Ohio