Department of Radiology’s advancements in imaging science

Imaging science is dedicated to exploring and advancing magnetic resonance imaging (MRI), computed tomography (CT), ultrasound, single photon emission computed tomography (SPECT), positron emission tomography (PET) and X-ray. The main interests of the group are DCE-MRI of tumors, cardiovascular contrast agents, magnetic resonance angiography (MRA), angiogenesis and molecular imaging. In addition to research within the aforementioned areas, the imaging science team conducts web-based conferencing with a number of collaborators, including the Ohio Supercomputer Center (OARnet), NIH/Clinical Center and biomedical informatics.

Facilities and Equipment

Wright Center

Wright Center of Innovation in Biomedical Imaging

Wright Center of Innovation in Biomedical Imaging

Dr. Michael V. Knopp received a $9.1 million Third Frontier Grant from Ohio Governor Bob Taft and $8 million from BRTT (the Biomedical Research and Technology Transfer award) to create the Wright Center of Innovation in Biomedical Imaging. The project is also known as the Biomedical Structural, Functional and Molecular Imaging Enterprise.

In addition to The Ohio State University, project collaborators include Case Western Reserve University, Philips Medical Systems of Highland Heights and the Ohio Supercomputer Center.

Concourse Building Martha MorehouseOur Location
WCI-BMI: Concourse Building
Martha Morehouse Medical Plaza
2050 Kenny Road
Columbus, OH 43221

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Program Director:
Michael V. Knopp, MD, PhD


Animal Imaging

WCI-BMI: Animal Imaging

WCI-BMI: Animal Imaging

The 4.7T/40cm MRI facility was created as part of the Ohio Cellular and Molecular Imaging Consortium (OCMIC) with the goal to advance state-of-the-art technology for animal imaging at the molecular, cellular and system level, to serve as a resource for medical research, biotechnology advances and pharmaceutical development, and for probing in-vivo gene function, disease processes and therapeutic applications including drug delivery and trials. The goal of the consortium is to facilitate inter-institutional collaboration between academic institutions in Ohio and technology transfer to Industry.

Wiseman HallOur Location
Animal MRI Facility (4.7T)
N113 Wiseman Hall
400 W. 12th Ave.
Columbus, OH 43210

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Program Director:
Petra Schmalbrock, PhD 


Imaging Core Lab

WCI-BMI: Imaging Core Laboratory

WCI-BMI: Imaging Core Laboratory

The Imaging Core Laboratory (ICL) through the Wright Center of Innovation at The Ohio State University performs visual reads, quantification, lesion tracking, perfusion and metabolic mapping, pharmacokinetic analysis, quantification of lesion heterogeneity, 3D segmentation and rendering in addition to conventional methodologies such as RECIST/WHO, volume tracking and morphologic characterization.

Imaging Core LabOur Location
Imaging Core Lab (ICL)
Wright Center of Innovation in Biomedical Imaging
395 W. 12th Ave., Room 414
Columbus, OH 43210

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Program Director:
Michael V. Knopp, MD, PhD



Microimaging Lab

WCI-BMI: Microimaging Lab

WCI-BMI: Microimaging Lab

The Biomedical Research Tower (BRT) is a 10-story, 403,000-square-foot facility housing more than 180,000 square feet of lab space. The BRT is the largest research facility on The Ohio State University campus, nearly doubling the amount of biomedical research space on campus.

The Microimaging Laboratory is housed within the lower level of the BRT. It serves as part of the advanced structural, functional and molecular animal imaging infrastructure. The facility is part of the Wright Center of Innovation in Biomedical Imaging resources/services.

BRTOur Location
Microimaging Lab
Wright Center of Innovation in Biomedical Imaging
460 W. 12th Ave., 0080 BRT, Box #41
Columbus, OH 43210

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Program Director:
Michael V. Knopp, MD, PhD



Molecular Imaging Agent Laboratory

WCI-BMI: Molecular Imaging Agent Laboratory

WCI-BMI: Molecular Imaging Agent Laboratory

The Molecular Imaging Agent Laboratory is housed within the Biomedical Research Tower on the seventh floor. The facility is part of the Wright Center of Innovation in Biomedical Imaging Resources and Services.

The laboratory, led by Dr. Michael Tweedle, pursues problems in cancer diagnosis and therapy using biochemical in-vivo imaging. The goal is hyper-effective cancer therapy through biochemically personalized treatment.

BRTOur Location
Microimaging Lab
Wright Center of Innovation in Biomedical Imaging
460 W. 12th Ave., 0080 BRT, Box #41
Columbus, OH 43210

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Program Director:
Michael F. Tweedle, PhD

Mutation and selection makes human cancer heterogeneous with respect to specific protein expressions and biochemical pathways used for growth and metastasis. The heterogeneity in phenotype results in the eventual failure of treatments targeted at a specific proteins and pathways. Hence targeted therapeutics are only effective in subsets of patients, who themselves usually fail treatment eventually. Current research projects are aimed at this fundamental problem.

Our Imaging Science Faculty

Our Imaging Science Faculty

Imaging Science Staff

Imaging Science Staff

Nuclear Medicine Technologists
Research Scientists
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Research Associates
Research Assistants