Innovations in vascular surgery at Ohio State


The Department of Surgery's research efforts are focused on key areas of interest that promise to yield significant results in the understanding of disease and the improvement of clinical care.

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We have placed a renewed emphasis on our academic tradition at Ohio State. Faculty in our division have interests in clinical outcomes research, health care policy, administration and financing, basic and translational stroke mechanisms and stem cell therapy for limb ischemia. Our research coordinator maintains a prospective database of all procedures for use in retrospective reviews and outcomes studies.

Areas of interest by faculty member

Areas of interest by faculty member

Hosam El Sayed, MD, PhD

Associate Professor of Clinical Surgery
Associate Program Director, Vascular Surgery Fellowship Program


Hosam El Sayed, MD, PhD, has research interests in outcome clinical research, complex aortic endograft therapy for thoracic and abdominal aortic disease, endovascular lower extremity revascularization, evaluation and adoption of new technologies and therapies in vascular surgery.

Hosam.Elsayed@osumc.edu
614-293-8536

Michael Go, MD

Medical Director, Vascular Surgery University Hospital East
Associate Professor of Clinical Surgery


Dr. Go has opportunities for residents to participate in clinical outcomes research or retrospective chart review studies. In addition, there are opportunities to participate in prospective trials of stem cell therapy for limb ischemia and platelet-rich plasma therapy in vascular graft infections. He participates as a Co-Investigator in an NIH-funded R01 project investigating the role of magnetic resonance elastography in the diagnosis and management of abdominal aortic aneurysms. Dr. Go is experienced in techniques of carotid intima media thickness measurement and brachial artery reactivity testing, providing these services through the Ross Heart Hospital Vascular Lab as a core resource for researchers throughout the OSU campus and for several multicenter trials.

Michael.Go@osumc.edu
614-293-8536

Mounir Haurani, MD

Assistant Professor of Clinical Surgery

Dr. Haurani has a research interest in endovascular surgery and clinical outcomes studies as well as serving as the PI or Sub-PI on several clinical trials and registries. His current projects include a studies on the outcomes after distal bypass revisions, amputations, utilization of technician's time in the vascular lab, review of the indications for and results of upper extremity and lower extremity arterial duplex.

Mounir.Haurani@osumc.edu
614-293-8536

Cameron Rink, PhD

Associate Professor of Surgery

Dr. Rink has expanded the Division’s scientific focus to include the basic mechanisms of stroke infarct evolution and exciting translational applications of oxygen and nutrient therapy to treat stroke.  His laboratory is interested in under-standing the specific role of molecular oxygen in stroke pathology.  Fundamental to this pursuit is the mechanistic understanding of how oxygen serves brain tissue as both a substrate for life-sustaining glucose metabolism, and in a setting of cerebral ischemia as a catalyst for pathological oxidative stress.  In pursuing this objective, we have established several novel in vitro and in vivo models to study hypoxic-ischemic cell death, reperfusion injury biology, and by correcting the hypoxia component of stroke, the unique contribution of oxygen to ischemic brain injury.  Research efforts span basic to translational science, with an emphasis on cutting-edge scientific tools such as electron paramagnetic resonance imaging for non-invasive oxymetry, and laser capture micro-dissection for cell and site specific resolution of stroke biology.

614-366-3806/293-4722

Significance of brain tissue oxygenation and the arachidonic acid cascade in stroke

Oxygen-sensitive outcomes and gene expression in acute ischemic stroke

Bhagwan Satiani, MD, MBA

Professor of Clinical Surgery
Director, FAME Faculty Leadership Institute
Health System Director, Non-Invasive Vascular Services

Dr. Satiani is interested in having residents participate in the growing area of research related to the economic consequences of our medical decisions. This includes cost of specific procedures, appropriateness of diagnostic testing, and efficiency of care. With the advent of value-based compensation and reimbursement and ‘bundled’ care, future practitioners will be asked to do more with less. Research is needed to influence clinicians to adopt the most cost-efficient ways to practice and to provide policy makers with factual information. There are opportunities particularly in the non-invasive vascular laboratory and other high volume areas.

Bhagwan.Satiani@osumc.edu
614-293-8536

Jean Starr, MD

Professor of Clinical Surgery
Health System Director, Endovascular Services
Program Director, Vascular Surgery Fellowship Program


Dr. Starr has a research interest in endovascular surgery and clinical outcomes studies, in addition to serving as the local Principal Investigator for several multicenter and NIH trials and a local prospective investigation.  Her current projects several Vascular Quality Initiative (SVS VQI) projects, investigation of radial artery and femoral access complications, carotid duplex criteria for LVAD patients, and vascular surgical site infections. She also leads local, regional, and national advocacy efforts for women in surgery.

Jean.Starr@osumc.edu
614-293-8536

Patrick Vaccaro, MD, MBA

Director, Division of Vascular Diseases and Surgery
Luther M. Keith Professor of Surgery


Dr. Vaccaro’s research interests are in clinical outcome studies pertaining to all aspects of vascular surgery.  He is also interested in the business aspects of healthcare and cost analysis studies.

Patrick.Vaccaro@osumc.edu
614-293-8536
Current industry sponsored trials

Performance of the Treovance Stent-Graft with Navitel Delivery System

PI: Mounir Haurani, MD

Sponsor: Boston Medical

BEST-CLI trial

PI: Jean Starr, MD

Sponsor: New England Research Institutes/National Institutes oh Health

CREST-2

PI: Jean Starr, MD

Sponsor: The Mayo Clinic/National Institutes of Neurological Disorders and Stroke

Effects of Prevena Therapy

PI: Jean Starr, MD

Sponsor: KCI Medical

iGOT Neuroprotection

PI: Cameron Rink, PhD

Sponsor: The National Institutes of Health

Nanotechnology

PI: Cameron Rink, PhD

Sponsor: The National Institutes of Health

Neo Legacy HUD use

PI: Jean Starr, MD

Sponsor: CVRx Inc.

Valiant Evo US Clinical Trial

PI: Jean Starr, MD

Sponsor: Medtronic

Pending industry sponsored trials

Comparing the Boston Scientific RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty

PI: Jean Starr, MD

Sponsor: Boston Scientific

Tack Optimized Balloon Angioplasty Study

PI: Hosam El Sayed, MD

Sponsor: Intact Vascular

TIDE

PI: Jean Starr, MD

Sponsor: New England Research Institutes/National Institutes of Health

Recently closed industry sponsored trials

Stenting of the Superficial Femoral and Proximal Popliteal Arteries

PI: Jean Starr, MD

Sponsor: Boston Scientific

Zenith TX2 Low Profile TAA Endovascular Graft

PI: Jean Starr, MD

Sponsor: Cook Inc.

Contact

Dawn Sagle
Division Administrator

614-293-8536
Dawn.Sagle@osumc.edu

701 Prior Hall
376 West 10th Avenue

Columbus, OH 43210