Don Benson

Don Benson, MD,PhD

  • Hematology

Appointments: (614) 293-3196

About Me

I’m an oncologist and hematologist caring for patients with multiple myeloma, amyloidosis and other blood cancers. I’m also actively involved in clinical and laboratory-based research to develop new treatments and approaches to these conditions. I serve as an associate professor of clinical internal medicine for The Ohio State University and as Head of Translational Research in the division of hematology at the OSU Wexner Medical Center. In 2014 and 2017, I was rated in the top 10 percent of physicians in the nation for patient satisfaction.

We strive to deliver personalized care to our patients by taking into account not only their specific type of cancer but their desires and goals as well. Our research programs work toward developing novel treatments that harness and enhance the immune system’s ability to detect and kill cancer cells. Natural killer cells are a type of immune cell capable of eliminating cancer cells. Much of the research we do focuses on augmenting or recovering the function of these cells.

I’ve published 87 peer-reviewed clinical, translational and laboratory based research papers in journals such as Journal of Clinical Oncology, Blood, PNAS, Cancer Cell, Clinical Cancer Research and many others. My team’s work has been presented at international scientific meetings around the world, and has
been funded by the National Cancer Institute, the American Cancer Society, Pelotonia and other sources.

I feel blessed to work at The James because of my team. I believe that the collective care we provide to patients is much greater than our individual contributions. Our patients have the added benefit of the entire institution supporting them in their fight to overcome cancer.


  • Rated in the top 10 percent of physicians in the nation for patient satisfaction, 2017

Specialties and conditions I treat

  • Hematology
  • Bone Marrow Transplantation
  • Multiple Myeloma
  • Amyloidosis
  • Lymphomas
  • Blood Cancers

Locations where I practice

Please note: Not all physicians schedule patients at each listed location. Please call the “Schedule an appointment” number shown above for scheduling assistance.

Education and training

Medical Degree

Northeastern Ohio Universities College of Medicine


Internal Medicine
University of Virginia Health System
7/1/2000 - 6/30/2003

More about my work

My background


Ohio State University Wexner Medical Center
7/1/2003 - 6/30/2006

Board Certifications

American Board of Internal Medicine

American Board of Internal Medicine (Subspecialty: Medicine Oncology)

My Department

Internal Medicine

My Division


Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the University requires annual disclosures from all faculty members with external interests related to their University responsibilities.

As of 03/28/2017, Dr. Benson has reported no financial relationships with medical device, research and/or drug companies.