Payal Desai

Payal Desai, MD

  • Hematology
  • Physician What's this? A physician, or doctor, is extensively trained to diagnose and treat complex medical problems. Often, physicians focus their practice on certain disease categories, treatment methods or patient types. Physicians can diagnose and treat illness, prescribe medication, offer medical consultation and advice, perform surgery and more.

Appointments: (614) 293-9441

About Me

I am a hematologist and my area of expertise is treating patients with sickle cell disease, a non-cancerous blood disease that can cause a variety of very serious complications for patients. At the OSUCCC – James, I am a part of a multidisciplinary team that treats these patients and provides them with unique opportunities for clinical trials of alternative therapies to treat their disease.

I serve as director of sickle cell research for The Ohio State University and am co-director of the Sickle Cell Program. In addition, I’m involved in a variety of related national organizations, including the boards of the American Society of Hematology Sickle Cell Disease Guideline Committee and the Sickle Cell Adult Provider Network. I also serve an associate professor of internal medicine for Ohio State and have authored more than a dozen articles for publication as well as presented nearly 40 abstracts and presentations.

What I enjoy most working at The James is the tremendous desire of people to work together to provide optimal care for patients. We put aside our egos, collaborate and strive toward providing the best care and treatment for our patients in an effort to improve lives and outcomes.

Additional Languages I Speak

  • Gujarati

Procedures and Conditions I Treat

  • Hematology
  • Hemophilia B
  • Hemophilia A
  • Purpura, Thrombotic Thrombocytopenic
  • von Willebrand Diseases
  • Benign Hematology
  • Anemia, Sickle Cell
  • Blood Coagulation
  • Thrombocytopenia
  • Thrombophilia
  • Thrombosis

Locations Where I Practice

Please note: Not all physicians schedule patients at each listed location. Please call the “Schedule an appointment” number shown above for scheduling assistance.

Education and Training


Internal Medicine
University of Louisville Hospital
7/1/2007 - 6/30/2009


University of North Carolina Hospitals
7/1/2009 - 6/30/2012

More About My Work

My Background

Board Certifications

American Board of Internal Medicine

American Board of Internal Medicine (Subspecialty: Hematology)

My Department

Internal Medicine

My Division


Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the University requires annual disclosures from all faculty members with external interests related to their University responsibilities.

As of 03/26/2018, Dr. Desai has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office at 614-293-8000.

  • AstraZeneca