The most common of biliary disorders is gallstone disease.

Biliary (bile) disorders encompass a variety of conditions affecting the bile ducts or gallbladder. Some can cause a problem with the flow of bile from the liver to the small intestines.

The most common of the biliary disorders is gallstone disease. Other diseases include sphincter of Oddi dysfunction (spasm of the muscles that regulate flow from, or narrowing of the opening where the bile and pancreatic ducts empty into the small intestine), primary biliary cirrhosis, primary sclerosing cholangitis (a condition that slowly damages the bile ducts within and outside of the liver), bile duct cancer (cholangiocarcinoma), gallbladder cancer and cancer involving the head of the pancreas.

Scarring can also block the bile ducts, which can lead to liver failure (secondary biliary cirrhosis). This is most commonly related to stones retained in the bile duct. A rare form of bile duct disease called biliary atresia occurs in infants and is the most common reason for liver transplants in children in the United States.

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