Center for Physical Medicine and Rehabilitation

WorthenChaudhariMotion Analysis and Recovery Laboratory

Associate Director, Department of Physical Medicine and Rehabilitation, Assistant Professor, Department of Dance – Complementary Appointment

Department of Physical Medicine and Rehabilitation
Center for Clinical and Translational Science

Dodd Hall
480 Medical Center Dr.
Columbus, OH 43210
Phone: 614-293-6281
Email: Lise.Worthen-Chaudhari@osumc.edu

Background: My lab applies a design-thinking approach to research and development of motor learning interventions, such as locomotor training and interactive neurotechnology. Our optimal goal is to extend the ceiling of recovery for individuals with neuromotor deficits. Toward this end, we apply biomechanical quantification techniques to investigate best practices for applying creative paradigms and emerging technologies – from arts, gaming, or other disciplines traditionally categorized in the creative sector – to improve human recovery and health.

Research/Clinical interests: spinal cord injury, chemotherapy-induced peripheral neuropathy, traumatic brain injury, parkinson disease, multiple sclerosis, stroke, biomechanics, motor control, interactive design, neurorehabilitation, dance

Current Research Projects:

  1. Eccentric Training to Improve Human SCI: To evaluate effectiveness of an eccentrically-focused treadmill training program for retraining of gait among individuals with spinal cord injury.
  2. Clinical Trial of a Rehabilitation Game – SuperBetter: Evaluate the feasibility of the computer game SuperBetter to be an intervention tool helping patients with mild to moderate brain injury transition from hospital care to self-management at home.
  3. Embedded Arts: Randomized control trial (RCT): Evaluate effect of creative engagement such as creative arts and immersive video on motor outcomes in neurorehabilitation.
  4. Training Frontal Plane Eccentric Motor Control to Improve Locomotion After iSCI: To evaluate effectiveness of an eccentrically-focused treadmill training program for retraining of gait among individuals with spinal cord injury.
  5. Niche Trial: Navigated Inhibitory rTMS to Contralesional Hemisphere Trial (NICHE): A, prospective, multi-center study combining navigated brain stimulation- guided repetitive transcranial magnetic stimulation of the healthy hemisphere with standardized task oriented rehabilitation in patients with post-stroke motor impairment.
  6. Interactive Music for Neurorecovery : To develop and test an interactive responsive music program that provides knowledge of performance in a concurrent auditory feedback scheme to individuals undergoing locomotor training.

Active Funding: SCI Rehabilitation Research Seed Funding : To seed research of SCI at Ohio State, NIH NINDS, Center for Personalized Health Care, OSUWMC, Neilsen Foundation - SCRIPTS Pilot Grant, Grants for Research and Creative Activity in the Arts & Humanities, Fraternal Order of Eagles Community Org

Selected Publications:

  1. Worthen-Chaudhari, L., Schmiedeler, J. P., & Basso, D. M. (2015). Training conditions that best reproduce the joint powers of unsupported walking. Gait & Posture.
  2. Maung D, Crawfis R, Gauthier L, Worthen-Chaudhari L, Lowes L, Borstad A, McPherson R (2014) Development of Recovery Rapids: A Game for Cost Effective Stroke Therapy, Foundations of Digital Games, Proceedings of the 9th Annual Conference (Exemplary Full Paper), Ft Lauderdale, FL, April 3-7, 2014.
  3. Worthen-Chaudhari L, Basso M, Schmiedeler J, Bing J (2014) A New Look at an Old Problem: Defining Weight Acceptance During Human Walking at Different Speeds. Gait & Posture 39.1,588-592.
  4. Jaffe, J., Lowes, L., Borstad, A., Worthen-Chaudhari, L., Crawfis, R., Maung, D., Siles, A. & Gauthier, L (2014) Delivery of Constraint-Induced Movement Therapy Through a Video Game for Individuals with Hemiparesis Post-Stroke. The Journal of Alternative and Complementary Medicine, 20(5), A119-A120.
  5. Worthen-Chaudhari L, Whalen C, Swendal C, Bockbrader MA, Haserodt S, Smith R, Bruce MK, Mysiw W (2013) A feasibility study using interactive graphic art feedback to augment acute neurorehabilitation therapy. NeuroRehabilitation 33.3, 481-490. CV 2014 Lise Worthen-Chaudhari Page 3 of 14
  6. Maung D, Crawfis R, Gauthier L, Worthen-Chaudhari L, Lowes L, Borstad A, McPherson R (2013) Games for Therapy: Defining a Grammar and Implementation for the Recognition of Therapeutic Gestures, Foundations of Digital Games, Proceedings of the 8th Annual Conference, Chania, Crete, Greece, May 14-17, 2013.
  7. Lowes, L. P., Alfano, L. N., Yetter, B. A., Worthen-Chaudhari, L., Hinchman, W., Savage, J.,Samona, P., Flanigan, K. M., & Mendell, J. R. (2012). Proof of Concept of the Ability of the Kinect to Quantify Upper Extremity Function in Dystrophinopathy. PLoS currents, 5.
  8. Worthen-Chaudhari, L (2012) New Partnerships between Dance and Neuroscience: Embedding the Arts for Neurorecovery, Dance Research, 29(2), 467-494.
  9. Yadev V., Schmiedeler J. P., McDowell S., Worthen-Chaudhari L (2010) Quantifying Age-Related Differences in Human Reaching while Interacting with a Rehabilitation Robotic Device, Applied Bionics and Biomechanics, 7(4), 289-299.
  10. Van der Loos H. F. M., L. Worthen-Chaudhari, D. Schwandt, D. M. Bevly, S.A. Kautz (2010) A split-crank bicycle ergometer uses servomotors to provide programmable pedal forces for studies in human biomechanics. IEEE Trans Neural Sys & Rehab Eng. 4/2010, Epub ahead of print.
  11. Brewer, Bambi, S.K. McDowell, L.C. Worthen-Chaudhari (2007) Post-Stroke Upper Extremity Rehabilitation: A Review of Robotic Systems and Clinical Results. Topics in Stroke Rehabilitation 14(6), 22-44.
  12. Worthen L.C., C. M. Kim, S. A. Kautz, H. L. Lew, B. J. Kiratli, and G. S. Beaupre (2005) Key characteristics of walking correlate with bone mineral density in volunteers with post-stroke walking deficits. Journal of Rehabilitation Research and Development 42(6), 761-768. 13)

PubMed articles

Education:
1994 BFA University of Massachusetts, Amherst
1999 MS University of Massachusetts, Amherst
2011 MFA The Ohio State University

Editorial Activities:
2011-current Certified Clinical Research Coordinator, Association of Clinical Research Professionals
2000-2011 Certified Exercise Specialist, American College of Sports Medicine
Nov 2015 Invited attendee The 13th Annual National Academies Keck Futures Initiative (NAKFI) conference, “Art and Science, Engineering, and Medicine Frontier Collaborations: Ideation, Translation & Realization”, Huntington Beach, CA.

Society/Memberships:
2014-present Brain Games planning committee, Neurological Institute, The Ohio State University
2013 Awards Council Member, Gait and Clinical Movement Analysis Society
2007-2010 ASC International Action Advisory Committee for The Ohio State University
2004-present Member, American Society of Biomechanics
2004 Selection committee for Women in Neuroscience Lifetime Achievement Awards
2003 Organizing committee for IEEE sponsored conference, RoMan, addressing Robot-Human interface
1996-present Member, International Association for Dance Medicine and Science

Honors/News:
Ohio State Study Shows 'Embedded Arts' Interactive Technology Helps Patients in Neurohabilitation Therapy

Columbus Business First, “2015 Health Care Heros Honorees”. Worthen-Chaudhari: Innovation Award. July 9, 2015.

The Ohio State University Alumni Magazine. “The art of healing”. Nicole Craft. July 7, 2015.

King 5-TV-NBC4, Seattle, WA. “Turning rehabilitation into an art form”. Jean Enersen . May 1, 2015

WJXT – News 4 Jax, Graham Media Group, Jacksonville, FL “Interactive art rehab motivates patients”. Jodi Mohrmann, March 19, 2015.

MDLinx: Neurology. “Ohio State study shows embedded arts interactive technology helps patients in neurorehabilitation therapy”. March 18, 2015.

KFDX-3- NBC, Texas & Oklahoma (Texoma). “Interactive Art Rehab”. Staff writer. March 5, 2015.

Minecraft Game Fan Zone, a minecraft news syndication. “Health Beat: Interactive art rehab”. March, 2015. Minecraftworlds.net.

WFMZ-TV: Health Beat, Eastern PA & Western NJ. “Health Beat: Interactive Art Rehab”. Feb 26, 2015. Online audience: 623,352 Broadcast audience: 32,404

WWSB-TV – ABC, Tampa, FL. “Ohio State study shows embedded arts interactive technology helps patients in neurorehabilitation therapy”. Feb 26, 2015. Broadcast audience: 19,693

KOAM-TV – CBS, Joplin, MO. “Ohio State study shows embedded arts interactive technology helps patients in neurorehabilitation therapy”. Feb 24, 2015 Broadcast audience: 36,709

Ivanhoe Broadcast News: Medical Breakthroughs. “Interactive Art Rehab”. Feb 23, 2015.

ABC12 WJRT, Flint MI. “Art Rehabilitation is Changing the Lives of Therapy Patients”. Christina Burkhart. Feb 20, 2015.

NewsChannel 5, Scripps TV group, ScrippsMedia.com. “Interactive Art Rehab”. Feb 10, 2015

Washington Post. "Brain-stimulating device may aid recovery of stroke victims". Amy Ellis Nutt. Nov 24, 2014.

PT in Motion. "Washington Post: Brain-stimulating device may aid recovery of stroke victims". Nov 24, 2014.

ScienceDaily. “Repetitive transcranial magnetic stimulation studied for stroke rehab”. Staff writer. Nov 21, 2014.

China Topix. Chinatopix.com. "New System Uses the Arts as a Form of Physical Rehab". Dino Lirios. Sept 5, 2014. Online audience 92,908

Yahoo News via Live Science. Yahoo - ABC News. "As Patients Create Art, They Recover". Lise Worthen-Chaudhari. Sept 3, 2014. Online audience: 59 million

Independent Living Solutions: Rehabilitation Solutions, England & Wales. "New technology uses art to help disabled individuals". Staff writer for "Latest Rehab News". Sept 8, 2014.

LiveScience. "As Patients Create Art, They Recover". Lise Worthen-Chaudhari. Aug 22, 2014. Online audience: 1.68 million

Physical Therapy Products, The Allied Media Network. "Computer Program Uses Art to Aid in Rehabilitation for Patients with Nervous System Injuries". Staff writer. June 20, 2014.

Columbus Dispatch. "Therapy-turned-art Aims to Heal Mentally, Physically". Madeline Winer. The Dispatch Printing Company. June 7, 2014. Print audience: 131,276 Online audience: 654,465

Good Day Columbus. WTTE-TV/28. Fox News 28. "Turtle Around Town: Columbus Arts Festival". June 6, 2014. Broadcast audience: 54,402

Images & Voices of Hope (IVOH). "Researchers find video games like SuperBetter are helping to decrease anxiety, depression". Mallary Jean Tenore. May 8, 2014.

Wall Street Journal. "Different Way to Treat Depression: Games". Dow Jones & Company. Angela Chen. May 5, 2014. Print audience: 1.5 million Online audience: 4.3 million

Rehabilitation Management, Allied Media Network. "Interactive Technology Helps Neurorehab Patients to Create "Healing Art"". Staff reporter. March 28, 2014. CV 2014 Lise Worthen-Chaudhari Page 9 of 14 Print audience: 20,000

Stroke Connection Magazine. "Artists in Recovery". Staff writer. March 12, 2014. Print audience: 100,000 Online audience: 526,783

CityScene Magazine. CityScene Media Group. "The Art of Rebuilding". Stephan Reed. 2014.

WCMH-TV - NBC4, Columbus OH. "Science and Art Combine for Therapy at OSU’s Wexner Medical Center". Ellie Merritt. Feb 27, 2014. Broadcast audience: 66,556; Online audience: 213,200

Big Data Future blog. "OSU Wexner Medical Center and Big Data”. Karlie Frank. Feb 11, 2014.

O'Reilly Radar. O'Reilly Media. "Reducing Hospital Readmissions using Data Science and a Social Twist". Michael Gold and Lise Worthen-Chaudhari. Aug 15, 2013.

O'Reilly Media. "Reducing hospital readmissions using data science and a social twist - an interview with Michael Gold and Lise Worthen-Chaudhari". Andy Oram. Aug 13, 2013.

InForm Alumni Magazine, The Ohio State University Department of Dance. “Dance Wellness and Rehabilitaiton”. Meghan Durham. Oct, 2011.

Christopher and Dana Reeve Foundation blog “SCI patients create art through movement”. Submitted by Dr. Michele Basso, posted by staff writer. March 24, 2010.

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