CHTNThe Cancer Diagnosis Program of the National Cancer Institute (NCI) initiated the Collaborative (AKA Cooperative) Human Tissue Network (CHTN) grant in 1987. The Ohio State University was an original NCI grantee for this program and 2016 was our 30th year of CHTN funding. The major goal of the Collaborative Human Tissue Network is to facilitate the use of human tissues in biomedical research for basic and applied scientists from academia, industry and government to accelerate the advancement of scientific discoveries, as well as progress in cancer diagnosis and treatment. The Collaborative Human Tissue Network uses a prospective biospecimen procurement model rather than a biobanking model and works directly with investigators to determine the appropriate tissue sources (e.g. surgery, autopsy and transplant) in order to tailor tissue-processing methods to meet the research needs of the specific investigator. The Collaborative Human Tissue Network obtains human tissues and fluids from remnant materials removed from medically indicated surgical resections, autopsies and other procedures.

The Tissue Procurement Service (TPS) is a supporting service of the Collaborative Human Tissue Network.

MAPCHTN Divisions

The CHTN is comprised of five adult divisions based on geographical regions and one pediatric division that manages all investigator requests for pediatric specimens. The Midwestern Division, based at The Ohio State University and directed by Leona W. Ayers, MD, a professor in the Department of Pathology, includes Illinois, Indiana, Iowa, Michigan, Minnesota, Missouri, Ohio, West Virginia and Wisconsin, as well as Canada.

midwesterndivisionMidwestern Division

The CHTN divisions work both independently with individual investigators and together as a seamless operation to fulfill requests that are difficult to serve by any single division. The CHTN's unique informatics system allows each division to effectively communicate and network the needs of its investigators to all CHTN divisions. This tissue procurement network can collaboratively facilitate and fulfill an investigator's biospecimen request.

CHTN Application

Fees for Collaborative Human Tissue Network members

Fees for Collaborative Human Tissue Network members

Processing Fees

Because the Collaborative Human Tissue Network is an NCI supported resource, investigators are only charged a low processing fee for each sample to offset the costs of collecting, handling and preparing the specimens in accordance with the detailed requirements of the investigator. A sample is defined as one processed piece of a specimen, regardless of the sample size or type of processing. Each investigator is also responsible for all shipping costs.

The processing fees are as follows:
  • $50 processing fee per sample for investigators located at academic and government lab sites
  • $180 processing fee per tissue sample for investigators located at commercial organizations
  • $180 processing fee for prospectively-collected fluid sample for investigators located at commercial organizations
  • $75 processing fee/reassigned ("banked") fluid sample for investigators located at commercial organizations

Additional Service Fees

Additional services can be provided to investigators upon request. These fees are applicable to both academic and commercial investigators.

HE slide (from paraffin-embedded block)   $9 
Repeat HE slide (from paraffin-embedded block)
Unstained slide (from paraffin-embedded block) 
Repeat unstained slide (from paraffin-embedded block)
Cryostat-cut, stained slide (from frozen block)
Repeat cryostat-cut, stained slide (from frozen block)
First cut, cryostat-cut, unstained slide (from frozen block)
Each additional cryostat-cut, unstained slide (from frozen block)     
20 micron section
Ribbons and scrolls
Touch preps 

Investigators may request chart reviews for a minimal fee starting at $60. Other special handling and processing may be available for $25 per hour (minimum of $25).

Shipping charges are the responsibility of the investigator and are determined by the courier utilized. This charge will vary according to the weight and priority status of the shipment.

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