Obsessive Compulsive Disorder

Obsessive Compulsive Disorder

Deep Brain Stimulation (DBS) Therapy for Obsessive Compulsive Disorder (OCD)

Purpose of Study: This study plans to enroll up to 10 subjects who have been diagnosed with obsessive compulsive disorder (OCD). Once consented, the participants will undergo a positron emission tomography/computerized tomography (PET/CT) scan, electroencephalography (EEG) with event-related potentials (ERP), and cognitive assessments prior to the DBS surgery. After surgery, participants will repeat the PET/CT scan, EEG/ERP and cognitive assessments every six months for two years. Five study visits are required for the study. Additional visits may be required if the PET/CT scan, EEG/ERP, and cognitive assessments cannot be scheduled or completed on the same day.


Eligibility Criteria: Patients who are candidates and are scheduled for deep brain stimulation (DBS) surgery for treatment-resistant OCD under FDA approval of HDE #H050003 will be approached and asked to participate in this research study. There is no additional eligibility criterion.


Status of Study: Open to Enrollment


Principal Investigator: Ali Rezai, MD


Contact:
Phone: Amelia Hargrove, 614-366-6639
Email: amelia.hargrove@osumc.edu


Sponsor: Ali Rezai, MD

Reclaim Deep Brain Stimulation (DBS) Therapy for Obsessive Compulsive Disorder

Purpose of Study: The Food and Drug Administration (FDA) gave approval of the Humanitarian Device Exemption (HDE), a humanitarian-use device for Medtronic Reclaim Therapy to Medtronic, Inc. (HDE# H050003). Medtronic Reclaim Deep Brain Stimulation (DBS) Therapy for obsessive compulsive disorder (OCD) delivers electrical stimulation to areas in the brain to help control symptoms of treatment-resistant OCD. The Medtronic Reclaim DBS Therapy is indicated for bilateral stimulation of a specific region of the brain (anterior limb of the internal capsule) in conjunction with OCD medications for treatment of chronic, severe, treatment-resistant OCD in adult patients who have failed at least three selective serotonin reuptake inhibitor medications. DBS is used as an alternative to anterior capsulotomy (different type of surgery) that is indicated for this condition.


Principal Investigator: Ali Rezai, MD


Contact:
Amelia Hargrove
Phone: 614-366-6639
Email: amelia.hargrove@osumc.edu

Women's Behavioral Health

Women's Behavioral Health

Enhancing Sexuality After Cancer

Addressing the Unmet Needs of Cancer Patients and Survivors


Purpose of the Study: This clinical research project offers a psychological intervention designed to prevent or reduce the sexual difficulties and stress that can follow gynecologic and breast cancer diagnosis and treatment.


Description: Over the past 20 years, our team has conducted a great deal of research with gynecologic and breast cancer patients and survivors. This research has taught us two important things. First, sexual issues are common and difficult for gynecologic and breast cancer patients. Second, until now, there have been very few resources available to these patients coping with sexual difficulties and stress following their diagnosis and treatment.

Unlike other treatments for sexual concerns or difficulties, this one is designed specifically for women treated for breast or gynecologic cancer.  Individual or group treatment will be provided to all those who participate.  All study-related treatment sessions and information are strictly confidential.

Therapy sessions take place over five months.  Study participation will also include 4 assessment interviews that will take place over the course of nine months.

There is no cost to you. The treatment associated with this study will be provided free-of-charge. In fact, all participants will be compensated for the time spent completing the study assessments.


Eligibility Criteria: If you have been diagnosed with breast or gynecologic cancer, are married or partnered, and are at least 21 years old, you may be eligible to participate.


Contact:
Nichole Storey
Phone: 614-685-8754
Email: nichole.storey@osumc.edu

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