Davis Heart and Lung Research Institute

Vice Chair of Research of the Department of Surgery
Director of the Laboratory of Molecular Medicine
Associate Director of the Davis Heart and Lung Research Institute
Professor of Surgery and of Molecular & Cellular Biochemistry

College of Medicine
Department of Surgery, Division of General and Gastrointestinal Surgery and Division of Colorectal Surgery

545/565 Davis Heart and Lung Research Institute
473 W. 12th Ave.
Phone: 614-247-7658
Fax: 614-247-7818
Research Interests:
• Tissue injury and repair (skin, brain and heart)
• miRNA biology
• Redox signaling
• Tissue oxygenation
• Oxidant

Current Research: In the skin, the Sen group works on wound healing – both experimentally as well as clinically. In the brain, specific focus is directed toward stroke biology and related neurodegeneration. The Sen group has identified the alpha-tocotrienol form of vitamin E as a major protector against stroke-induced injury to the brain.

In the heart, emphasis is on post-infarction myocardial remodeling with emphasis on miRNA biology.

Across all of these programs, the Sen groups uses advanced MRI, echocardiographic as well hyperspectral imaging approaches. 

Active Funding: He is the PI on two active NIH awards: one from the NIGMS on wound healing and the other from NINDS on vitamin E. In addition, he holds an R13 award from NIH-NIAMS.

PubMed articles


PhD: University of Kuopio
Post-Doc: University of California, Berkeley

Bowditch Award Nominee, American Physiological Society (2004)
Honorary Member, Alpha Epsilon Delta National Honors Society (2003)
Citation of Recognition, Mayor of Columbus, City of Columbus, Ohio (September 2002)
Outstanding Contribution to Education Award, The Ohio State University Medical Center (September 2002)
Fellow of the American College of Nutrition (2001)

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