Comprehensive Spine Center

FarhadiFrancisAssistant Professor, Department of Neurological Surgery 
Director, Division of Degenerative and Deformity Spine
Director, Spinal Surgery Fellowship Program

College of Medicine
Department of Neurological Surgery

Clinic:
Comprehensive Spine Center
543 Taylor Ave., Suite 1029
Columbus, OH 43203
614-293-2225

Office:
N1021 Doan Hall
410 W. 10th Ave.
Columbus, OH 43210
614-366-4961
Francis.Farhadi@osumc.edu


Research interests: 

  • Degenerative spinal conditions
  • Minimally invasive spinal surgery
  • Spinal deformity
  • Spinal cord injury
  • Peripheral nerve injury
  • Stem cells

Current Research: Dr. Farhadi’s laboratory research is focused on developing and validating small animal models of central and peripheral nervous system injury that can be used to test the potential of stem-cell implantation to enhance functional recovery. Cultured stem cells differentiated along myelinating glial paths — either oligodendroglial or Schwann cell — are being transplanted at various stages and time points following injury along with growth factor support to determine whether locomotor activity and other functional outcome measures can be improved. The results and conclusions drawn from such studies will help guide the rational design of human trials evaluating the clinical potential of stem-cell therapies.

Enrolling Clinical Trials: 
  • Spinal Cord Injury Neuroprotection with Glyburide - NCT02524379
  • Multicenter Study to Assess the Efficacy and Safety of VX-210 in Subjects with Acute Traumatic Cervical Spinal Cord Injury - NCT02669849
  • Multicenter, Prospective, Single Arm Study of Patients Undergoing a Two or Three Level ACDF Using ViviGen® Cellular Bone Matrix in Conjunction with Cervical Allograft Spacers and DePuy Synthes Spine Anterior Cervical Plate Systems - NCT02814825
  • Prospective Multicenter Follow-up of Patients Undergoing Instrumented Thoracic and Lumbar Arthrodesis Supplemented by the Implanet Jazz SystemTM - NCT02411799
  • Prospective Follow-up of Elderly Patients Undergoing Instrumented Lumbar Arthrodesis Supplemented by the Implanet Jazz System 
  • Radiographic and Clinical Outcomes Following Unilateral or Bilateral Posterior Fixation in Minimally Invasive Transforaminal Lumbar Interbody Fusions - NCT01996371
  • Spinal Arthrodesis and Spinal Arthroplasty Database - NCT01979094

Education:
MPH: University of London
MD/PhD: McGill University

Postgraduate Training:  
Residency: Neurological Surgery, University of Toronto 
Fellowship: Peripheral Nerve, Barnes-Jewish Hospital
Fellowship: Complex Spine Surgery, Jackson Memorial Hospital

Honors/News:
  • 2017: Research grant for biomechanical cadaver study in collaboration with the University of Iowa (Implanet America Inc)
  • 2013: Lawrence J. Mervis, MD, Teacher of the Year Award, Department of Neurological Surgery

Editorial Activities/Medical Journals:

  • J Neurotrauma, 2013-present
  • Spinal Cord, 2013-present
  • World Neurosurgery, 2015-present
Recent Publications:
  • Viswanathan V, Manoharan SR, Do H, Minnema A, Shaddy SM, Elder JB, Farhadi HF. Clinical and Radiologic Outcomes Following Fenestration and Partial Wall Excision of Idiopathic Intradural Spinal Arachnoid Cysts Presenting with Myelopathy. World Neurosurgery. 2017 May 31.
  • Kunte H, Farhadi HF, Sheth KN, Simard JM, Kronenberg G. Sulfonylureas--a novel treatment to reduce tissue damage after acute spinal cord injury? Lancet Neurol. 2015 Apr;14(4):352.
  • Manoharan SR, Shaw AB, Arnold CA, Farhadi HF. Infiltrative intramuscular myxoma of the cervical spine: a case report. Spine J. 2015 Jan 1;15(1):e1-4.

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