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The Department of Urology is committed to developing research that will translate into more effective treatments for patients with urologic disorders.

View Non-cancer Clinical Trials

Urology Non-Cancer Research Studies

Project Title: Morbidity and Mortality in Medicaid Patients Who Underwent Radical Cystectomy for Bladder Cancer
IRB Number: 2017C0156
PI: Bahnson
Co-Pi: Shabsigh, Hendawi

Project Title: Immediate vs Delayed Surgical Intervention for Penile Fracture
IRB Number: 2016E0635
PI: Bellows

Project Title: Barriers to Repeat Treatment with Intradetrusor OnabotulinumtoxinA Injection
IRB Number: 2016H0306
PI: Bellows
Co-Pi: Ebert

Project Title: Patterns of Consultation for Difficult Urethral Catheterization and Rates of Iatrogenic Trauma
IRB Number: 2017H0420
PI: Bellows
Co-Pi: Cooper, Szabo

Project Title: The Urology Boot-Camp: A Pilot Curriculum to Enhance Medical Student Procedural Competency
IRB Number: 2017B0530
PI: Bellows
Co-Pi: Lee, Sharp, Cooper

Project Title: Urology Ultrasound Training Curriculum
IRB Number: 2016H0087
PI: Box
Co-Pi: Wan

Project Title: Robotic-assisted laparoscopic partial nephrectomy for benign disease: tips, tricks, and outcomes
IRB Number: 2016H0341
PI: Box
Co-Pi: Sourial, Zynger, Miller

Project Title: Evaluation of Image Improvement from Ultrasound Training Curriculum Using the Brightness Mode Quality Ultrasound Imaging Examination Technique (B-QUIET)
IRB Number: 2017E0713
PI: Box
Co-Pi: Wan

Project Title: Simple Nephrectomy: Does Surgery Relieve Symptoms?
IRB Number: 2017H0003
PI: Box
Co-Pi: Sourial, Szabo, Zynger, Miller, Dall

Project Title: Effects of Steep Trendelenburg on Intraocular Pressure and Retinal Nerve Fiber Layer in Robotic Prostatectomy
IRB Number: 2015H0247
PI: Box
Co-Pi: Shabsigh, Sharp, Todd, Khemees, Gridley, Sourial

Project Title: Outcomes of artificial urinary sphincter erosion in patients with male incontinence
IRB Number: 2015H0063
PI: Jenkins
Co-Pi: Ebert

Project Title: Correlation between Stent Culture and Urine Culture in Ureteral Stent Patients
IRB Number: 2015H0383
PI: Knudsen
Co-Pi: Dall

Project Title: Survey of Antiplatelet and Anticoagulant Practice Patterns in Kidney Stone Surgery
IRB Number: 2016E0384
PI: Knudsen
Co-Pi: Ebel

Project Title: Safety of Continuing Aspirin Therapy at the Time of Percutaneous Nephrolithotomy (PCNL)
IRB Number: 2016E0577
PI: Knudsen
Co-Pi: Ebel

Project Title: Resident experience with ultrasound guided access and patient dose reduction techniques in percutaneous nephrolithotomy.
IRB Number: 2017E0600
PI: Knudsen
Co-Pi: Ebel

Project Title: The EDGE Consortium: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy in Patients with Moderate Risk of Postoperative Infection
IRB Number: 2017H0055
PI: Knudsen

Project Title: Prospective Trial of a Reusable Digital Flexible Ureteroscope vs a Single-Use Flexible Ureteroscope in the Treatment of Urolithiasis: An EDGE Consortium Clinical Trial
IRB Number: 2017H0118
PI: Knudsen

Project Title: Reducing Intra-Operative Fluoroscopy Time in Percutaneous Nephrolithotomy
IRB Number: 2017H0393
PI: Knudsen
Co-Pi: Sourial, Todd

Project Title: Use of the qSOFA Score for Prediction of ICU Admission Due to Sepsis After Percutaneous Nephrolithotomy
IRB Number: 2017H0406
PI: Knudsen
Co-Pi: Sourial

 

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2017 Publications

Alpert SA. Commentary to ‘Proximal hypospadias repair with bladder mucosal graft. Our 10 years experience’. J Pediatr Urol. 2017 Jun;13(3):295.

Borza T, Jacobs BL, Montgomery JS, Weizer AZ, Morgan TM, Hafez KS, Lee CT, Li BY, Min HS, He C, Gilbert SM, Helm JE, Lavieri MS, Hollenbeck BK, Skolarus TA. No differences in population-based readmissions after open and robotic-assisted radical cystectomy: implications for post-discharge care. Urology. 2017 Mar 4. pii: S0090-4295(17)30229-7.

Cooper J, Chisolm D, McLeod DJ. Sociodemographic characteristics, health literacy, and care compliance in families with spina bifida. Glob Pediatr Health. 2017 Dec 6; 4:2333794X17745765.

Dall CP, Sharp DS, Zynger DL. Benign Müllerian inclusions in lymphadenectomies for renal cell carcinoma: a radiologic and pathologic mimic of metastases. Clin Genitourin Cancer. 2017 Apr 26. pii: S1558-7673(17)30101-5.

Daneshmand S, Patel S, Lotan Y, Pohar K, Trabulsi E, Woods M, Downs T, Huang W, Jones J, O'Donnell M, Bivalacqua T, DeCastro J, Steinberg G, Kamat A, Resnick M, Konety B, Schoenberg M, Jones JS; Flexible Blue Light Study Group Collaborators, Bazargani S, Cookson M, Cross B, Lallas CD, Djaladat H, Gomella L, Johnson M, McKiernan J, Mann M, Merrill M, Nielsen M, Pierorazio P, Pruthi R, Sankin A, Schuckman A, Shabsigh A, Shah JB, Smith A, Stratton K, Taylor J, Weight C, Wenske S. Efficacy and safety of Blue Light Flexible Cystoscopy with Hexaminolevulinate (HAL) in the surveillance of bladder cancer: A Phase III, comparative, multi-center study. J Urol. 2017 Dec 2. pii: S0022-5347(17)78004-4. doi: 10.1016/j.juro.2017.11.096.

Diaz DA, Mortazavi A, Lee CT. A potential role for adjuvant chemotherapy and radiotherapy for patients with high-risk bladder cancer treated with cystectomy in the United States.

JAMA Surg. 2017 Nov 29:e174592. doi: 10.1001/jamasurg.2017.4592.

Fuchs ME, Atkinson TH, DaJusta DG. Cystic dysplasia of the testis in an intraabdominal undescended testicle. Urol Case Rep. 2017 May 20;13:143-144.

Fuchs ME, Beecroft N, Dajusta DG, McLeod DJ. The association between BXO and obesity in boys undergoing circumcision. Glob Pediatr Health. 2017 Nov 24;4:2333794X17742749.

Fuchs ME, Beecroft N, Dajusta DG, McLeod DJ. Is delayed phase CT imaging necessary after blunt renal trauma in children? Urology. 2017 Nov 23. pii: S0090-4295(17)31214-1.

Fuchs ME, Lu PL, Vyrostek SJ, Teich S, Alpert SA. Factors predicting complications after sacral neuromodulation in children. Urology. 2017 Sep;107:214-217.

Gonzalez DO, Cooper JN, McLeod DJ. Effect of bladder augmentation on VP shunt failure rates in spina bifida. J Pediatr Rehabil Med. 2017 Dec 11;10(3-4):249-255.

Gonzalez DO, Cooper JN, Minneci PC, Deans KJ, McLeod D. Reducing the number of anesthetic exposures in the early years of life: circumcision and myringotomy as an example.

Clin Pediatr (Phila). 2017 Aug 1:9922817727466.

Gridley CM, Knudsen BE. Digital ureteroscopes: technology update. Res Rep Urol. 2017 Jan 27;9:19-25.

Habous M, Muir G, Soliman T, Farag M, Williamson B, Binsaleh S, Elhadek W, Mahmoud S, Ibrahim H, Abdelwahab O, Abdelrahman Z, Abdelkader M, Jenkins LC, Mulhall JP. Outcomes of variation in technique and variation in accuracy of measurement in penile length measurement. Int J Impot Res. 2017 Nov 27. doi: 10.1038/s41443-017-0013-3.

Helfand AM, Beach R, Hadj-Moussa M, Krishnan N, He C, Montgomery JS, Morgan TM, Weizer AZ, Hafez K, Lee CT, Stoffel JT, Skolarus TA. Treatment of ureteral anastomotic strictures with reimplantation and survival after cystectomy and urinary diversion. Urol Oncol. 2017 Jan;35(1):33.e1-33.e9.

Kamat AM, Bellmunt J, Galsky MD, Konety BR, Lamm DL, Langham D, Lee CT, Milowsky MI, O'Donnell MA, O'Donnell PH, Petrylak DP, Sharma P, Skinner EC, Sonpavde G, Taylor JA 3rd, Abraham P, Rosenberg JE. Erratum to: Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of bladder carcinoma. J Immunother Cancer. 2017 Sep 28;5(1):80. doi: 10.1186/s40425-017-0280-z.

Kamat AM, Bellmunt J, Galsky MD, Konety BR, Lamm DL, Langham D, Lee CT, Milowsky MI, O'Donnell MA, O'Donnell PH, Petrylak DP, Sharma P, Skinner EC, Sonpavde G, Taylor JA 3rd, Abraham P, Rosenberg JE. Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of bladder carcinoma. J Immunother Cancer. 2017 Aug 15;5(1):68. doi: 10.1186/s40425-017-0271-0.

Jaeger CD, Rule AD, Mehta RA, Vaughan LE, Vrtiska TJ, Holmes DR 3rd, McCollough CM, Ziegelmann MJ, Herrera Hernandez LP, Lieske JC, Krambeck AE. Endoscopic and pathologic characterization of papillary architecture in struvite stone formers. Urology. 2016 Apr;90:39-44.

Kamat AM, Colombel M, Sundi D, Lamm D, Boehle A, Brausi M, Buckley R, Persad R, Palou J, Soloway M, Witjes JA. BCG-unresponsive non-muscle-invasive bladder cancer: recommendations from the IBCG. Nat Rev Urol. 2017 Apr;14(4):244-255.

Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G. Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. J Clin Invest. 2017 Mar 1;127(3):830-842.

Knoll T, Daels F, Desai J, Hoznek A, Knudsen B, Montanari E, Scoffone C, Skolarikos A, Tozawa K. Percutaneous nephrolithotomy: technique. World J Urol. 2017 Sep;35(9):1361-1368.

Kominsky HD, Bashline M, Eun D, Pontari MA, Mydlo JH, Reese AC. Use of age and medical comorbidity to assess long-term other-cause mortality risk in a cohort of men undergoing prostate biopsy at an academic medical center. Urology. 2017 Feb;100:169-174.

Langston JP, Duszak R Jr, Orcutt VL, Schultz H, Hornberger B, Jenkins LC, Hemingway J, Hughes DR, Pruthi RS, Nielsen ME. The expanding role of advanced practice providers in urologic procedural care. Urology. 2017 Aug;106:70-75.

Lavery HJ, Zaharieva B, McFaddin A, Heerema N, Pohar KS. A prospective comparison of UroVysion FISH and urine cytology in bladder cancer detection. BMC Cancer. 2017 Apr 7;17(1):247.

Li B, Haridas B, Jackson AR, Cortado H, Mayne N, Kohnken R, Bolon B, McHugh KM, Schwaderer AL, Spencer JD, Ching CB, Hains DS, Justice SS, Partida-Sanchez S, Becknell B. Inflammation drives renal scarring in experimental pyelonephritis. Am J Physiol Renal Physiol. 2017 Jan 1;312(1):F43-F53.

Liaw A, Rickborn L, McClung C. Incidence of urethral stricture in patients with adult acquired buried penis. Adv Urol. 2017;2017:7056173.

Lodwick D, Asti L, Deans K, Minneci P, McLeod D. Variation in practice patterns for the management of newborn spina bifida in the United States. Urology. 2017 Feb;100:207-212.

Lomas DJ, Jaeger CD, Krambeck AE. Profile of the ammonium acid urate stone former based on a large contemporary cohort. Urology. 2017 Apr;102:43-47.

Lu PL, Asti L, Lodwick DL, Nacion KM, Deans KJ, Minneci PC, Teich S, Alpert SA, Yacob D, Di Lorenzo C, Mousa HM. Sacral nerve stimulation allows for decreased antegrade continence enema use in children with severe constipation. J Pediatr Surg. 2017 Apr;52(4):558-562.

Matlaga BR, Chew B, Eisner B, Humphreys M, Knudsen B, Krambeck A, Lange D, Lipkin M, Miller NL, Monga M, Pais V, Sur RL, Shah O. Ureteroscopic laser lithotripsy: a review of dusting vs fragmentation with extraction. J Endourol. 2017 Nov 27. doi: 10.1089/end.2017.0641.

Maurice MJ, Sundi D, Schaeffer EM, Abouassaly R. Risk of pathological upgrading and up staging among men with low risk prostate cancer varies by race: results from the National Cancer Database. J Urol. 2017 Mar;197(3 Pt 1):627-631

Nguyen HT, Shah ZK, Mortazavi A, Pohar KS, Wei L, Jia G, Zynger DL, Knopp MV. Non-invasive quantification of tumour heterogeneity in water diffusivity to differentiate malignant from benign tissues of urinary bladder: a phase 1 study. Eur Radiol. 2017 May;27(5):2146-2152.

Osawa T, Ambani SN, Olugbade K Jr, Skolarus TA, Weizer AZ, Montgomery JS, He C, Hafez KS, Hollenbeck BK, Lee CT, Montie JE, Palapattu GS, Morgan TM. Potential implications of shortening length of stay following radical cystectomy in a pre-ERAS population. Urology. 2017 Apr;102:92-99.

Preece J, Ching C, Yackey K, Jayanthi V, McLeod D, Alpert S, DaJusta D. Indicators and outcomes of transfer to tertiary pediatric hospitals for patients with testicular torsion. J Pediatr Urol.  2017 Aug;13(4):388.e1-388.e6.

Preece J, Prasad V, McLeod D. Pediatric xanthogranulomatous cystitis: the first described case in a pre-pubertal male and review of the literature. Pediatr Dev Pathol. 2017 Jul-Aug;20(4):330-334.

Tosoian JJ, Almutairi F, Morais CL, Glavaris S, Hicks J, Sundi D, Humphreys E, Han M, De Marzo AM, Ross AE, Tomlins SA, Schaeffer EM, Trock BJ, Lotan TL. Prevalence and prognostic significance of PTEN loss in African-American and European-American men undergoing radical prostatectomy. Eur Urol. 2017 May;71(5):697-700.

Roth B, Jayaratna I, Sundi D, Cheng T, Melquist J, Choi W, Porten S, Nitti G, Navai N, Wszolek M, Guo C, Czerniak B, McConkey D, Dinney C. Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis. Oncotarget. 2017 May 23;8(21):34205-34222.

Schlomer BJ, Keays MA, Grimsby GM, Granberg CF, DaJusta DG, Menon VS, Ostrov L, Sheth KR, Hill M, Sanchez EJ, Harrison CB, Jacobs MA, Huang R, Burgu B, Hennes H, Baker LA. Trans-scrotal near infrared spectroscopy as a diagnostic test for testis torsion in pediatric acute scrotum: a prospective comparison to gold standard diagnostic test study. J Urol. 2017 Apr 6. pii: S0022-5347(17)45410-3.

Sourial MW, Richard PO, Bettez M, Jundi M, Tu LM. Mitomycin-C and urethral dilatation: A safe, effective, and minimally invasive procedure for recurrent vesicourethral anastomotic stenoses. Urol Oncol. 2017 Dec;35(12):672.e15-672.e19.

Sourial MW, Richard PO, Morisset J, Jundi M, Tu LM. Retrograde leak point pressure measurement improves outcomes of the Virtue male sling for postprostatectomy incontinence. Can Urol Assoc J. 2017 Jul;11(7):E271-E276.

Sundi D, Schaeffer EM. Progress in prognosis and prediction for men with prostate cancer. Eur Urol. 2017 Jul;72(1):32-33

Terrier JE, Paparel P, Gadegbeku B, Ruffion A, Jenkins LC, N'Diaye A. Genitourinary injuries after traffic accidents: analysis of a registry of 162, 690 victims. J Trauma Acute Care Surg. 2017 Jun;82(6):1087-1093.

Tretter EM, Ebel JJ, Pohar KS, Zynger DL. Does the gross prosector impact pT3 subclassification or lymph node counts in bladder cancer? Hum Pathol. 2017 Mar;61:190-198.

Vilanova-Sánchez A, Ching CB, Gasior AC, Diefenbach K, Wood RJ, Levitt M. Image of the Month: clinical features in a newborn with covered cloacal exstrophy. European J Pediatr Surg Rep. 2017 Jan;5(1):e57-e59.

Whitaker EE, Wiemann BZ, DaJusta DG, Alpert SA, Ching CB, McLeod DJ, Tobias JD, Jayanthi VR. Spinal anesthesia for pediatric urological surgery: Reducing the theoretic neurotoxic effects of general anesthesia. J Pediatr Urol. 2017 Aug;13(4):396-400.

Wood RJ, Reck-Burneo CA, Dajusta D, Ching C, Jayanthi R, Bates DG, Fuchs ME, McCracken K, Hewitt G, Levitt MA. Cloaca reconstruction: a new algorithm which considers the role of urethral length in determining surgical planning. J Pediatr Surg. 2017 Oct 12. pii: S0022-3468(17)30644-9

Research Notables

Tariq Khemees, MD

khemees• Tariq Khemees, MD won the Best Clinical Poster entitled “Comparison of Oncologic Outcomes After Open Versus Robotic-Assisted Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma” at the 91st Annual Meeting of the North Central Section of the AUA

• Dr. Khemees also received the Urology Care Foundation 2018 Research Scholar Award. 
Project title: Improving Androgen Deprivation Therapy by Synthetic Lethal Metabolic Targeting. The research will be conducted at Carbone Cancer Center, University of Wisconsin as a 2018 SUO (Society of Urologic Oncology) Fellow under the mentorship of Dr. David Jarrard.

 

 

 

 

 

 

 

 

 

Sundi Debasish  MD 1572 5xDebasish Sundi, MD 

• Debasish Sundi, MD received a 2-year Research Scholar Award from the Urology Care Foundation: the Official Foundation of the American Urological Association for his  project: MDSC Depletion via Ibrutinib as a Strategy to Increase Sensitivity of Bladder Cancer to Immune Checkpoint Blockade in a Murine Allograft Model 

 

 

 

 

 

 

 

 

 

 Dr. Mohamed Hendawi

• Dr. Mohamed Hendawi won “Best Poster Award” at the annual North Central Section of the AUA meeting for his project, The Impact of Neoadjuvant Chemotherapy for Muscle Invasive Bladder Cancer, a Retrospective Institution Experience.

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