Vice Dean for Research

mohler peterProfessor, Departments of Internal Medicine and Physiology
Director, Dorothy M. Davis Heart and Lung Research Institute
Chair, Department of Physiology and Cell Biology
William D. and Jacquelyn L. Wells Chair in Cardiovascular Research
The Ohio State University College of Medicine & Wexner Medical Center
 
473 W. 12th Ave.
Columbus, OH  43210

614-247-8610
Peter.Mohler@osumc.edu

Education:

PhD: University of North Carolina, 2000
BS: Wake Forest University, 1995

Honors:

  • Kavli Fellow of the U.S. National Academy of Sciences, Representative for Medicine and Physiology, 2009 - present
  • Pew Scholar in the Biomedical Sciences, Pew Charitable Trusts, 2007 - present
  • Worthington Fellowship, American Society of Cell Biology, 2000
  • Glaxo-Wellcome Graduate Award, 1998

Chapters in Books

Anderson ME and Mohler PJ. "Chapter 4: Structural and Molecular Basis of Ion Channel Function: Intracellular Signaling and Regulation of Cardiac Ion Channels." In Cardiac Electrophysiology: From Cell to Bedside. 5th ed. Edited by Zipes and Jalife. -. Philadelphia, PA: Elsevier, January 2008

H Gudmundsson, F Jareczek, and PJ Mohler. "Defects in ankyrin-based protein targeting pathways in human arrhythmia." In Heart rate and rhythm: Molecular basis, pharmacological modulation, and clinical implications. -. Philadelphia, PA: Elsevier, January 2010

TJ Hund, SR Cunha, and PJ Mohler. "Chapter 2: Principles of Cellular Architecture and Physiology with Applications in Electrophysiology." In Electrophysiological Disorders of the Heart. 2nd ed. Edited by Saksena and Camm. -. Philadelphia, PA: Elsevier, January 2010

S Hashemi and PJ Mohler. "Long QT, Short QT, and Brugada Syndromes." In Cardiology: An Illustrated Text/Reference. 2nd ed. Edited by Kanu Chatterjee. -. [unspecified]: Lippincott, January 2011

Conferences

Mohler PJ, Splawski I, Napolitano C, Bottelli G, Sharpe L, Timothy K, Priori SG, Keating MT, Bennett V. "A cardiac arrhythmia syndrome caused by loss of ankyrin-B function." Proc Natl Acad Sci., USA. (January 2004). 9137-9142

Mohler PJ, Rivolta I, Napolitano C, LeMaillet G, Lambert S, Priori SG, Bennett V. "Nav1.5 E1053K muta-tion causing Brugada Syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes." Proc Natl Acad Sci., USA. (January 2004). 17533-17538

Le Scouarnec S, Bhasin N, Vieyres C, Hund TJ, Cunha SR, Koval O, Marionneau C, Chen B, Wu Y, Demolombe S, Song LS, Le Marec H, Probst V, Schott JJ, Anderson ME, and Mohler PJ. "Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease." Proc Natl Acad Sci., USA. (January 2008). 15617-15622

Y Wu, Z Gao, B Chen, OM Koval, MV Singh, X Guan, TJ Hund, WJ Kutschke, S Sarma, IM Grumbach, XHT Wehrens, PJ Mohler, LS Song, ME Anderson. "Calmodulin kinase II is required for fight or flight sinoatrial node physiology." Proc Natl Acad Sci., USA. (January 2009). 5972-5977

CF Kline, HT Kurata, TJ Hund, SR Cunha, OM Koval, PJ Wright, M Christensen, ME Anderson, CG Nichols, and PJ Mohler. "Dual role of KATP channel C-terminal motif in membrane targeting and metabolic regulation." Proc Natl Acad Sci., USA. (January 2009). 1669-1674

Koval OM, Guan X, Wu Y, Joiner M, Gao Z, Chen B, Grumbach IM, Luczak ED, Colbran RJ, Song LS, Hund TJ, Mohler PJ, and Anderson ME. "The Cav1.2 β subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations." Proc Natl Acad Sci U S A. (January 2010). 4996-5000

Editorial Activities

Present Activities
  • Proceedings of the National Academy of Sciences
  • Journal of Neurogenetics
  • Journal of Molecular Biology
  • Journal of Biological Chemistry
  • FASEB Journal
  • European Heart Journal
  • Brain Research
  • Biochemistry
  • American Journal of Physiology (multiple journals)
  • Trends in Molecular Medicine
  • Trends in Microbiology
  • Molecular Pharmacology
  • Molecular and Cellular Neuroscience
  • Journal of Clinical Investigation
  • Journal of Cellular Biochemistry
  • Journal of Cardiovascular Pharmacology
  • Heart Rhythm
  • Frontiers in Pharmacology of Ion Channels and Channelopathies
  • Frontiers in Cardiac Electrophysiology
  • Expert Opinion on Drug Safety
  • Circulation Research
  • Circulation
  • Cardiovascular Research
  • British Journal of Pharmacology
  • American Journal of Cardiology
  • PLoS One
  • PLoS Biology
  • Journal of Physiology
  • Journal of Neuroscience
  • Clinical Chemistry and Laboratory Medicine
  • Journal of Molecular and Cellular Cardiology

Journal Articles

Browne CL, Creton R, Karplus E, Mohler PJ, Palazzo RE, Miller AL. "Analysis of the Ca2+ transient at nuclear envelope breakdown during the first cell cycle in dividing sea urchin eggs." Biological Bulletin. Vol. 191, (January 1996.): 5-16

Mohler PJ, Kreda SM, Boucher RC, Sudol M, Stutts MJ, Milgram SL. "Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50." The Journal of Cell Biology. Vol. 147, (January 1999.): 879-890

Goy MF, Oliver PM, Purdy KE, Knowles JW, Fox JE, Mohler PJ, Qian X, Smithies O, Maeda N. "Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide." Biochemical Journal. Vol. 358, (January 2001.): 379-387

Mohler PJ, Kultgen PL, Stutts MJ, Milgram SL. "Biochemical assays for studying indirect interactions between CFTR and the cytoskeleton." Methods in Molecular Medicine. Vol. 70, (January 2002.): 383-394

Mohler PJ, Gramolini AO, Bennett V. "The Ankyrin-B C-terminal Domain Determines Activity of Ankyrin-B/G Chimeras in Rescue of Abnormal Inositol 1,4,5- Trisphosphate and Ryanodine Receptor Distribution in Ankyrin-B (-/-) Neonatal Cardiomyocytes." Journal of Biological Chemistry. Vol. 277, (January 2002.): 10599-10607

Mohler PJ, Gramolini AO, Bennett V. "Ankyrins." The Journal of Cell Science. Vol. 115, (January 2002.): 1565-1566

Mohler PJ, Schott JJ, Gramolini AO, Dilly KW, Guatimosim S, DuBell WH, Song LS, Haurogne K, Kyndt F, Ali ME, Rogers TB, Lederer WJ, Escande D, LeMarec H, Bennett V. "Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death." Nature. Vol. 421, (January 2003.): 634-639

Wehrens XHT, Lehnart SE, Huang F, Vest JA, Reiken SR, Mohler PJ, Sun J, Guatimosim S, Song LS, Rosemblit N, D’Armiento JM, Napolitano C, Memmi M, Priori SG, Lederer WJ, Marks AR. "FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death." Cell. Vol. 113, (January 2003.): 829-840

Mohler PJ, Yoon WY, Bennett V. "Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes." Journal of Biological Chemistry. Vol. 279, (January 2004.): 40185-40193

Mohler PJ, Hoffman JA, Davis JQ, Abdi KM, Kim C, Jones SK, Davis LH, Roberts KF, Bennett V. "Isoform specificity among ankyrins: An amphipathic alpha-helix in the divergent regulatory domain of ankyrin-B interacts with the molecular co-chaperone Hdj1/Hsp40." Journal of Biological Chemistry. Vol. 279, (January 2004.): 25798-25804

Mohler PJ, Davis JQ, Davis LH, Hoffman JA, Michaely P, Bennett V. "InsP3 receptor localization and stability in cardiomyocytes requires interaction with ankyrin-B." Journal of Biological Chemistry. Vol. 279, (January 2004.): 12980-12987

Facemire CS, Mohler PJ, Arendshorst WJ. "Expression and relative abundance of short transient receptor potential channels in the rat renal microcirculation." American Journal of Physiology, Renal Physiology. Vol. 286, (January 2004.): F546-F551

Swift LL, Kakkad B, Boone C, Jovanovska A, Jerome WG, Mohler PJ, Ong DE. "Microsomal triglyceride transfer protein (MTP) expression in adipocytes: A new component in fat metabolism." FEBS Letters. Vol. 579, (January 2005.): 3183-3189

Mohler PJ, Lowe JS, Banks S. "Dysfunction in ankyrin-based cellular pathways and human cardiac arrhythmia." Future Cardiology. Vol. 1, (January 2005.): 363-371

Mohler PJ, Davis JQ, Bennett V. "Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac transverse-tubule/sarcoplasmic reticulum microdomain." Public Library of Science Biology (PLOS Biology). Vol. 3, (January 2005.): 423-

Mohler PJ, and Bennett V. "Defects in ankyrin-based cellular pathways in metazoan physiology." Frontiers in Bioscience. Vol. 10, (January 2005.): 2832-2840

Mohler PJ, and Bennett V. "Ankyrin-based cardiac arrhythmia: a new class of channelopathies due to loss of cellular targeting." Current Opinion in Cardiology. Vol. 20, (January 2005.): 189-193

Kline CF, and Mohler PJ. "Weighing in on molecular anchors: The role of ankyrins in cardiac channelopa-thies and human arrhythmia." Expert Review in Cardiovascular Therapy. Vol. 4, (January 2006.): 477-485

Braun NA, Mohler PJ, Weisgraber KH, Hasty AH, Linton MF, Yancey PG, Su YR, Fazio S, Swift LL. "Intra-cellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells." Journal of Lipid Research. Vol. 47, (January 2006.): 1176-1186

Mohler PJ. "Ankyrins and human disease: What the electrophysiologist should know." Journal of Cardiovascular Electrophysiology. Vol. 10, (January 2006.): 1153-1159

Grueter CE, Abiria SA, Dzhura I, Wu Y, Ham AJ, Mohler PJ, Anderson ME, Colbran RJ. "Calmodulin Kinase II facilitates L-type Ca2+ channels by beta subunit phosphorylation." Molecular Cell. Vol. 23, (January 2006.): 641-650

Cunha SR, and Mohler PJ. "Cardiac ankyrins: Essential components for development and maintenance of excitable membrane domains in heart." Cardiovascular Research. Vol. 71, (January 2006.): 22-29

Abdi KM, PJ Mohler, Davis JQ, Bennett V. "Isoform Specificity of Ankyrin-B: A site in the divergent C-terminal domain is required for intramolecular association." Journal of Biological Chemistry. Vol. 281, (January 2006.): 5741-5749

Hodson CA, Ambrogi IG, Scott RO, Mohler PJ, Milgram SL. "Polarized apical sorting of guanylyl cyclase C is specified by a cytosolic signal." Traffic. Vol. 7, (January 2006.): 1-9

Cunha SR, Bhasin N, Mohler PJ. "Targeting/stability of the Na/Ca exchanger in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B." Journal of Biological Chemistry. Vol. 282, (January 2007.): 4875-4883

Bhasin N, Cunha SR, Mudannayake M, Gigena MS, Rogers TB, Mohler PJ. "Molecular basis for PP2A regulatory subunit B56 alpha targeting in cardiomyocytes." American Journal of Physiology: Heart. Vol. 293, (January 2007.): H109-119

Li J, Marionneau C, Koval O, Zingman L, Mohler PJ, Nerbonne J, Anderson ME. "Calmodulin kinase II inhibition enhances ischemic preconditioning by augmenting ATP-sensitive K+ current." Channels. Vol. 1, (January 2007.): 387-394

Lehnart SE, Ackerman MJ, Brugada R, Benson DW Jr, Clancey CE, Donahue JK, George AL Jr, Grant AO, Groft SC, January CT, Lathrop DA, Lederer WJ, Makielski JC, Mohler PJ, Moss A, Nerbonne JM, Olson TM, Przywara DA, Towbin JA, Wang LH, Marks AR. "Inherited Arrhythmias--an NHLBI-ORD workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion transport function." Circulation. Vol. 116, (January 2007.): 2325-2345

Anderson ME, and Mohler PJ. "MicroRNA may have macro effect on sudden death." Nature Medicine. Vol. 13, (January 2007.): 410-411

Mohler PJ, Zhu MY, Blade AM, Ham AJ, Shelness GS, Swift LL. "Identification of a novel isoform of microsomal triglyceride transfer protein." Journal of Biological Chemistry. Vol. 282, (January 2007.): 26981-26988

Mohler PJ, Le Scouarnec S, Denjoy I, Lowe JS, Guicheney P, Caron L, Driskell IM, Schott JJ, Norris K, Leenhardt A, Kim RB, Escande D, Roden DM. "Defining the cellular phenotype of ‘ankyrin-B syndrome’ variants: Human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes." Circulation. Vol. 115, (January 2007.): 432-441

Mohler PJ, Healy JA, Xue H, Puca AA, Kline CF, Allingham RR, Kranias EG, Rockman HA, Bennett V. "Ankyrin-B Syndrome: Enhanced cardiac function balanced by risk of cardiac death and premature senescence." Public Library of Science (PLoS)One. Vol. 2, (January 2007.): e1051-

Mohler PJ and Wehrens XHT. "Mechanisms of human arrhythmia syndromes: Abnormal cardiac macromolecular interactions." Physiology. Vol. 22, (January 2007.): 342-350

Kizhatil K, Yoon WY, Mohler PJ, Davis LH, Hoffman JA, Bennett V. "Ankyrin-G and beta-2-spectrin collabo-rate in biogenesis of the lateral membrane of human bronchial epithelial cells." Journal of Biological Chemistry. Vol. 282, (January 2007.): 2029-2037

Erickson JR, Joiner MA, Guan X, Kutschke W, Yang J, Oddis CV, Bartlett RK, Lowe JS, Aykin-Burns N, Zimmerman MC, Spitz DR, Colbran RJ, Shea MA, Mohler PJ, Anderson ME. "A dynamic pathway for calcium- independent activation of CaMKII by methionine oxidation." Cell. Vol. 133, (January 2008.): 462-474

Cunha, SR, Le Scouarnec S, Schott JJ, and Mohler PJ. "Exon organization and novel alternative splicing of the human ANK2 gene: Implications for cardiac function and human cardiac disease." Journal of Molecular and Cellular Cardiology. Vol. 45, (January 2008.): 724-734

Cunha SR and Mohler PJ. "The Cardiac Cytoskeleton and Arrhythmia: An Unexpected Role for Protein 4.1R in Cardiac Excitability." Circulation Research. Vol. 103, (January 2008.): 779-781

Cunha SR and Mohler PJ. "Obscurin targets ankyrin-B and protein phosphatase A to the cardiac M-line." Journal of Biological Chemistry. Vol. 283, (January 2008.): 31968-31980

Thiel WH, Chen B, Hund TJ, Koval OM, Purohit A, Song LS, Mohler PJ, and Anderson ME. "Proarrhythmic defects in a ventricular myocyte model of Timothy Syndrome require calmodulin kinase II." Circulation. Vol. 118, (January 2008.): 2225-2234

Kline CF, Cunha SR, Lowe JS, Hund TJ, Mohler PJ. "Revisiting ankyrin-InsP3 receptor interactions: ankyrin-B associates with the cytoplasmic N-terminus of the InsP3 receptor." Journal of Cellular Biochemistry. Vol. 104, (January 2008.): 1244-1253

Hund TJ, Ziman AJ, Lederer WJ, and Mohler PJ. "The cardiac IP3 receptor: Uncovering the role of “the other” calcium-release channel." Journal of Molecular and Cellular Cardiology. Vol. 45, (January 2008.): 159-161

Hund TJ, Decker KF, Kanter E, Mohler PJ, Boyden PA, Schuessler RB, Yamada KA, and Rudy Y. "Role of activated CaMKII in abnormal calcium homeostasis and INa remodeling after myocardial infarction: Insights from mathematical modeling." Journal of Molecular and Cellular Cardiology. Vol. 45, (January 2008.): 420-428

Sedlacek K, Stark K, Cunha SR, Pfeufer A, Weber S, Berger I, Wichmann HE, Mohler PJ, Hengstenberg C, Jeron A. "Common genetic variants in ANK2 influence QT interval- results from the KORA study." Circulation: Cardiovascular Genetics. Vol. 1, (January 2008.): 93-99

Mohler PJ, and Anderson ME. "New insights into genetic causes of sinus node disease and atrial fibrillation." Journal of Cardiovascular Electrophysiology. Vol. 19, (January 2008.): 516-518

Lowe JS, Palygin O, Bhasin N, Hund TJ, Boyden PA, Shibata E, Anderson ME, Mohler PJ. "Voltage-gated Nav channel targeting in heart requires an ankyrin-G-dependent cellular pathway." Journal of Cell Biology. Vol. 180, (January 2008.): 173-186

Hund TJ and Mohler PJ. "Ankyrin-based targeting pathway regulates human sinoatrial node automaticity." Channels. Vol. 2, (January 2008.): 404-406

TJ Hund, PJ Wright, W Dun, JS Snyder, PA Boyden, and PJ Mohler. "Regulation of the ankyrin-B-based targeting pathway following myocardial infarction." Cardiovascular Research. Vol. 81, (January 2009.): 742-749

MD Christensen, W Dun, PA Boyden, ME Anderson, PJ Mohler, and TJ Hund. "Oxidized calmodulin kinase II regulates conduction following myocardial infarction: A computational analysis." Public Library of Science (PLoS) Computational Biology. Vol. 5, (January 2009.): e1000583-

Anderson ME and Mohler PJ. "Rescuing a failing heart: Think globally, treat locally." Nature Medicine. Vol. 15, no. 1. (January 2009.): 25-26

SR Cunha and PJ Mohler. "Ankyrin protein networks in membrane formation and stabilization." Journal of Cellular and Molecular Medicine. Vol. 13, (January 2009.): 4364-4376

SM Hashemi, TJ Hund, and PJ Mohler. "Cardiac ankyrins in health and disease." Journal of Molecular and Cellular Cardiology. Vol. 47, (January 2009.): 203-209

CF Kline and PJ Mohler. "From Fifth Business to Protagonist: the complex roles of ion channel anchors in cardiac arrhythmia." Drug Discovery Today: Disease Models. Vol. 6, (January 2009.): 63-69

B Chen, Y Wu, PJ Mohler, ME Anderson, and LS Song. "Local Control of calcium-induced calcium release in mouse sinoatrial node cells." Journal of Molecular and Cellular Cardiology. Vol. 47, (January 2009.): 706-715

MV Singh, A Kapoun, L Higgins, W Kutschke, JM Thurman, R Zhang, M Singh, J Yang, X Guan, JS Lowe, RM Weiss, K Zimmermann, FE Yull, TS Blackwell, PJ Mohler and ME Anderson. "CaMKII triggers cell membrane injury by inducing complement factor B gene expression in heart." J Clin Invest. Vol. 119, (January 2009.): 986-996

MJ Tuvim, AR Mospan, KA Burns, M Chua, PJ Mohler, E Melicoff, R Adachi, Z Ammar-Aouchiche, CW Davis, BF Dickey. "Synaptotagmin 2 couples mucin granule exocytosis to calcium signaling from the endoplasmic reticulum." The Journal of Biological Chemistry. Vol. 284, (January 2009.): 9781-9789

Z Gao, MV Singh, DD Hall, OM Koval, ED Luczak, MA Joiner, B Chen, Y Wu, AK Chaudhary, JB Martins, TJ Hund, PJ Mohler, LS Song, ME Anderson. "Catecholamine-independent heart rate increases require CaMKII." Circulation: Arrhythmia and Electrophysiology. (January 2010.): -

RM Wolf, CC Mitchell, MD Christensen, PJ Mohler, and TJ. Hund. "Defining new insight into atypical arrhythmia: a computational model of ankyrin-B-syndrome." American Journal of Physiology - Heart and Circulatory Physiology. Vol. 299, (January 2010.): H1505-H1514

CF Kline, TJ Hund, and PJ Mohler. "Ankyrin regulates KATP channel membrane trafficking and gating in excitable cells." Channels. Vol. 4, (January 2010.): 55-57

AL Leoni, B Gavillet, JS Rougier, C Marionneau, V Probst, S Le Scouarnec, JJ Schott, S Demolombe, P Bruneval, CLH Huang, WH Colledge, AA Grace, H Le Marec, AA Wilde, PJ Mohler, D Escande, H Abriel, F Charpentier. "Variable Nav1.5 protein expression from the WT allele controls phenotypic penetrance in the Scn5a+/- mouse model for conduction disease." Public Library of Science (PLoS) One. Vol. 5, (January 2010.): e9298-

TJ Hund, OM Koval, J Li, PJ Wright, L Qian, JS Snyder, H Gudmundsson, CF Kline, NP Davidson, N Cardona, MN Rasband, ME Anderson, and PJ Mohler. "A �IV spectrin/CaMKII signaling complex is essential for vertebrate membrane excitability in mice." Journal of Clinical Investigation. Vol. 120, (January 2010.): 3508-3519

MJ Ackerman and PJ Mohler. "Defining a new paradigm for human arrhythmia syndromes: Phenotypic manifestations of gene mutations in ion channel- and transporter-associated proteins." Circulation Research. Vol. 107, (January 2010.): 457-465

J Yang, J Huang, B Maity, Z Gao, R Lorca, H Gudmundsson, J Li, A Stewart, P Swaminathan, S Ibeawuchi, A Shepherd, C Chen, W Kutschke, PJ Mohler, DP Mohapatra, ME Anderson, and RA Fisher. "RGS6, a Modulator of Parasympathetic Activation in Heart." Circulation Research. Vol. 107, (January 2010.): 1345-1349

J Li, CF Kline, TJ Hund, ME Anderson, and PJ Mohler. "Ankyrin-B regulates Kir6.2 membrane expression and function in heart." The Journal of Biological Chemistry. Vol. 285, (January 2010.): 28723-28730

H Li, W Li, K Arun, PJ Mohler, ME Anderson, and I Grumbach. "Calmodulin kinase II is required for angiotensin-II mediated vascular smooth muscle hypertrophy." American Journal of Physiology- Heart and Circulatory Physiology. Vol. 298, (January 2010.): H688-H698

AV Glukhov, VV Fedorov, ME Anderson, PJ Mohler, and IR Efimov. "Functional Anatomy of the Murine Sinus Node: High resolution optical mapping of ankyrin-B heterozygous mice." American Journal of Physiology- Heart and Circulatory Physiology. Vol. 299, (January 2010.): H482-H491

H Gudmundsson, TJ Hund, PJ Wright, CF Kline, JS Snyder, L Qian, OM Koval, SR Cunha, M George, MA Rainey, FE Kashef, W Dun, PA Boyden, ME Anderson, H Band, and PJ Mohler. "EH domain proteins regulate cardiac membrane protein targeting." Circulation Research. Vol. 107, no. 1. (January 2010.): 84-95

TJ Hund and PJ Mohler. "Cardiac spectrins: Alternative splicing encodes functional diversity." Journal of Molecular and Cellular Cardiology. Vol. 48, (January 2010.): 1031-1032

SR Cunha and PJ Mohler. "Ankyrin-based Cellular Pathways for Cardiac Ion Channel and Transporter Targeting and Regulation." Seminars in Cell and Developmental Biology. (January 2010.): -

PJ Mohler. "Sodium channel traffic on the cardiac microtubule highway." Cardiovascular Research. Vol. 85, (January 2010.): 645-646

Gao, Z, Chen B, Joiner ML, Wu Y, Guan X, Koval OM, Chaudhary AK, Cunha SR, Mohler PJ, Martins JB, Song LS, ME Anderson. "If and SR Ca2+ release both contribute to pacemaker activity in canine sinoatrial node cells." Journal of Molecular and Cellular Cardiology. Vol. 49, (January 2010.): 33-40

W Li , H Li, PN Sanders, PJ Mohler, J Backs, EN Olson, ME Anderson, IM Grumbach. "The multifunctional Ca2+/calmodulin-dependent kinase II &[delta] (CaMKII&[delta]) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21." Journal of Biological Chemistry. (January 2010.): -

TJ Hund and PJ Mohler. "Differential roles for SUR subunits in KATP channel membrane targeting and regulation." American Journal of Physiology-Heart and Circulatory Physiology. (January 2010.): -

PJ Mohler and TJ Hund. "Role for CaMKII in cardiovascular health, disease, and arrhythmia." Heart Rhythm. (January 2010.): -

J Shan, A Kushnir, MJ Betzenhauser, S Reiken, J Li, SE Lehnart, N Lindegger, M Mongillo, PJ Mohler, and AR Marks. "Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice." Journal of Clinical Investigation. (January 2010.): -

Inventions and Patents

PJ Mohler. "Methods of Modulating Localization and Physiological Function of InsP3 Receptors." Patent No. 10/336,031

Contact

Division of Cardiovascular Medicine

Tim Rumfield 
Division Administrator 
Tim.Rumfield@osumc.edu
614-293-4967

Division’s office:
234 Davis Heart & Lung Research Institute
473 W. 12th Avenue
Columbus, OH 43210