Contact
Candice Askwith, PhD
Core Director
614-688-7943
askwith.1@osu.edu
Candice Askwith, PhD
Core Director
614-688-7943
askwith.1@osu.edu
The Physiology Core is located in 4118 Graves Hall.
Electrode patched on neuron
Recorded neuron filled with fluorescent dye
Recorded action potentials
Microelectrode in a brain slice
Available services:
Please see our Terms of Service and User Fee Structure for specifics regarding use of this core.
Vick JS, Askwith CC.
Neuropharmacology. 2015 Jul;94:36-41. doi: 10.1016/j.neuropharm.2014.12.012. Epub 2015 Jan 12.
PMID: 25592215
Effects of high- fat diet and gastric bypass on neurons in the caudal solitary nucleus.
Boxwell, A.J., Chen, Z., Mathes, C.M., Spector, A.C., Le Roux, C.W., Travers, S.P., Travers, J.B.
Physiol Behav. 2015 Dec 1;152(Pt B):329-39. doi: 10.1016/j.physbeh.2015.07.025. Epub 2015 Jul 26.
PMID: 26216080
Green JA, Schmid CL, Bley E, Monsma PC, Brown A, Bohn LM, Mykytyn K.
Mol Cell Biol. 2015 Oct 26;36(1):223-35. doi: 10.1128/MCB.00765-15. Print 2016 Jan 1.
PMID: 26503786
Gallego-Perez D, Otero JJ, Czeisler C, Ma J, Ortiz C, Gygli P, Catacutan FP, Gokozan HN, Cowgill A, Sherwood TW, Ghatak S, Malkoc V, Zhao X, Wang X, Adler A, Leong L, Wulff B, Wilgus TA, Askwith CC, Khanna S, Rink C, Sen C, Lee LJ*
Nanomedicine. 2016 Feb;12(2):399-409. doi: 10.1016/j.nano.2015.11.015. Epub 2015 Dec 19.
PMID: 26711960
Frey EN, Pavlovicz RE, Wegman CJ, Li C, Askwith CC.
PLoS One. 2013 Aug 14;8(8):e71733. doi: 10.1371/journal.pone.0071733. eCollection 2013.
PMID: 23977127
Primary cilia enhance kisspeptin receptor signaling on gonadotropin-releasing hormone neurons.
Koemeter-Cox AI, Sherwood TW, Green JA, Steiner RA, Berbari NF, Yoder BK, Kauffman AS, Monsma PC, Brown A, Askwith CC, and Mykytyn K.
Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10335-40. doi: 10.1073/pnas.1403286111. Epub 2014 Jun 30.
PMID: 24982149
p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1.
Tian J, Tep C, Benedick A, Saidi N, Ryu JC, Kim ML, Sadasivan S, Oberdick J, Smeyne R, Zhu MX, Yoon SO.
J Biol Chem. 2014 Nov 7;289(45):31458-72. doi: 10.1074/jbc.M114.589937. Epub 2014 Sep 24.
PMID: 25253694
Meyer K, Ferraiuolo L, Miranda CJ, Likhite S, McElroy S, Renusch S, Ditsworth D, Lagier-Tourenne C, Smith RA, Ravits J, Burghes AH, Shaw PJ, Cleveland DW, Kolb SJ, Kaspar BK.
Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):829-32. doi: 10.1073/pnas.1314085111. Epub 2013 Dec 30.
PMID: 24379375
Tep C, Lim TH, Ko PO, Getahun S, Ryu JC, Goettl VM, Massa SM, Basso M, Longo FM, Yoon SO.
J Neurosci. 2013 Jan 9;33(2):397-410. doi: 10.1523/JNEUROSCI.0399-12.2013.
PMID: 23303920
Changes in Spontaneous firing patterns of cerebellar Purkinje cells in p75 knockout mice.
Tian J, Tep C, Zhu MX, Yoon SO.
Cerebellum. 2013 Jun;12(3):300-3. doi: 10.1007/s12311-012-0439-6.
PMID: 23307658
Alexander JK, Cox GM, Tian JB, Zha AM, Wei P, Kigerl KA, Reddy MK, Dagia NM, Sielecki T, Zhu MX, Satoskar AR, McTigue DM, Whitacre CC, Popovich PG.
Exp Neurol. 2012 Aug;236(2):351-62. doi: 10.1016/j.expneurol.2012.04.018. Epub 2012 May 1.
PMID: 22575600
Structure and activity of the acid-sensing ion channels.
Sherwood TW, Frey EN, Askwith CC.
Am J Physiol Cell Physiol. 2012 Oct 1;303(7):C699-710. doi: 10.1152/ajpcell.00188.2012. Epub 2012 Jul 25.
PMID: 22843794
Sherwood TW, Lee KG, Gormley MG, Askwith CC.
J Neurosci. 2011 Jun 29;31(26):9723-34. doi: 10.1523/JNEUROSCI.1665-11.2011.
PMID: 21715637
Hester ME, Murtha MJ, Song S, Rao M, Miranda CJ, Meyer K, Tian J, Boulting G, Schaffer DV, Zhu MX, Pfaff SL, Gage FH, Kaspar BK.
Mol Ther. 2011 Oct;19(10):1905-12. doi: 10.1038/mt.2011.135. Epub 2011 Jul
PMID: 21772256
Foust KD, Wang X, McGovern VL, Braun L, Bevan AK, Haidet AM, Le TT, Morales PR, Rich MM, Burghes AH, Kaspar BK.
Nat Biotechnol. 2010 Mar;28(3):271-4. doi: 10.1038/nbt.1610. Epub 2010 Feb 28.
PMID: 20190738
Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs.
Hu H, Tian J, Zhu Y, Wang C, Xiao R, Herz JM, Wood JD, Zhu MX.
Pflugers Arch. 2010 Mar;459(4):579-92. doi: 10.1007/s00424-009-0749-9. Epub 2009 Nov 4.
PMID: 19888597
TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP.
FEBS Lett. 2010 May 17;584(10):1966-74. doi: 10.1016/j.febslet.2010.02.028. Epub 2010 Feb 14.
PMID: 20159015
Iscru E, Serinagaoglu Y, Schilling K, Tian J, Bowers-Kidder SL, Zhang R, Morgan JI, DeVries AC, Nelson RJ, Zhu MX, Oberdick J.
Mol Cell Neurosci. 2009 Jan;40(1):62-75. doi: 10.1016/j.mcn.2008.09.002. Epub 2008 Oct 1.
PMID: 18930827
Zinc activates damage-sensing TRPA1 ion channels.
Hu H, Bandell M, Petrus MJ, Zhu MX, Patapoutian A.
Nat Chem Biol. 2009 Mar;5(3):183-90. doi: 10.1038/nchembio.146. Epub 2009 Feb 8.
PMID: 19202543
NAADP mobilizes calcium from acidic organelles through two-pore channels.
Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang KT, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, Wyatt CN, Parrington J, Ma J, Evans AM, Galione A, Zhu MX.
doi: 10.1038/nature08030.
Tsvilovskyy VV, Zholos AV, Aberle T, Philipp SE, Dietrich A, Zhu MX, Birnbaumer L, Freichel M, Flockerzi V.
Gastroenterology. 2009 Oct;137(4):1415-24. doi: 10.1053/j.gastro.2009.06.046. Epub 2009 Jun 21.
PMID: 19549525
TRPC5 is a Ca2+-activated channel functionally coupled to Ca2+-selective ion channels.
Gross SA, Guzmán GA, Wissenbach U, Philipp SE, Zhu MX, Bruns D, Cavalié A.
J Biol Chem. 2009 Dec 4;284(49):34423-32. doi: 10.1074/jbc.M109.018192. Epub 2009 Oct 8.
PMID: 19815560
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