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Ernest Mazzaferri
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Ernest Mazzaferri Jr., MD, FACC, is medical director of Ohio State’s Richard M. Ross Heart Hospital and assistant professor of clinical medicine at The Ohio State University Medical Center.

Dr. Mazzaferri implanted the first Ventricular Partitioning Device (VPD) in the United States in March 2008, and to date has successfully placed more VPD’s in patients than any practitioner in the world. He received the Healthcare Heroes Award from Business First in 2009 for his work with Ohio State Medical Center’s STEMI program.

Dr. Mazzaferri earned his medical degree and completed his residency at The Ohio State University College of Medicine. He completed his general cardiology fellowship and chief cardiology fellowship at the University of Florida in Gainesville, Fla., and interventional cardiology fellowship at Ohio State’s Medical Center.

An invited presenter on a variety of cardiovascular topics, Dr. Mazzaferri has published numerous abstracts, articles and book chapters. Dr. Mazzaferri is a Fellow in the American College of Cardiology and was also a faculty member at Transcatheterier Cardiovascular Therapeutics in 2009, the premier global forum for interventional cardiology.

His clinical and research interests include adjunctive pharmacotherapy in the Cardiac Catheterization Lab and novel heart failure device implantation.


  • Rated in the top 10 percent of physicians in the nation for patient satisfaction, 2014

Medical Degree

  • M.D.
    Ohio State University College of Medicine


  • Internal Medicine
    Ohio State University Wexner Medical Center
    7/1/1999 - 6/30/2002

Specialties and conditions I treat

  • Interventional Cardiology
  • Cardiac Catheterization
  • Acute Coronary Syndrome
  • Percutaneous Coronary Intervention
  • Heart Attack
  • Clinical Trial
  • Cardiovascular Diseases
  • Coronary Care Units
  • Angioplasty, Balloon, Coronary
  • Coronary Angiography
  • Coronary Artery Disease
  • Heart Valve Diseases
  • Hypercholesterolemia
  • Hypertension

My videos

Locations where I practice

Please note: Not all physicians schedule patients at each listed location. Please call the “Schedule an appointment” number shown above for scheduling assistance.

More about my work

My background


  • Interventional Cardiology
    Ohio State University Wexner Medical Center
    7/1/2005 - 6/30/2006
  • Cardio Disease
    University of Florida School of Medicine
    7/1/2002 - 6/30/2005

Board Certifications

American Board of Internal Medicine

American Board of Internal Medicine (Subspecialty: Cardiovascular)

American Board of Internal Medicine (Subspecialty: Interventional Cardiology)

My Department

Internal Medicine

My Division

Cardiovascular Medicine