Director, Translational Research, Davis Heart and Lung Research Institute
Professor, Department of Internal Medicine, Divisions of Endocrinology, Diabetes and Metabolism and Cardiovascular Medicine
Dr. Lewandowski's research examines the metabolic basis of impaired function in the diseased heart, and the impact of altered cardiac metabolism on peripheral organs and systemic metabolism. Active research protocols assess genomic, transcriptional and posttranslational regulation of metabolic flux in normal and diseased hearts.
A hallmark of Dr. Lewandowski's research program is the application of NMR and stable isotope kinetics to assess enzyme activity, and to quantify metabolic flux, intracellular transport rates, and metabolite turnover within the intact beating heart.