Active Clinical Trials


Head and Neck Oncology


Loni Arese, PhD, SLP
– Expiratory Muscle Strength Training in Improving Bulbar Function and Quality of Life in Patients With Head and Neck Cancer
 
Matt Old, MD – A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Determine the Safety and Efficacy of GL-0817 (with Cyclophosphamide) for the Prevention of Recurrence in HLA-A2+ Patients with High-Risk Squamous Cell Carcinoma of the Oral Cavity, Clinical Trial OSU 16267
 
Matt Old, MD – Phase II Investigation of Adjuvant Combined Cisplatin and Radiation with Pembrolizumab in Resected HNSCC, Clinical Trial OSU 15184
 
Enver Ozer, MD – A Pilot Study Assessing Transoral Robotic Surgery (TORS) for Oral and Laryngopharyngeal Benign and Malignant Lesions Using the Da Vinci Robotic Surgical System 
 
James Rocco, MD, PhD – A  Phase II Study of Enzalutamide (NSC#766085) for Patients with Androgen Receptor Positive Salivary Cancers (ALLIANCE), Clinical Trial OSU Alliance-A091404
 
James Rocco, MD, PhD – Phase II Randomized Trial of Adjuvant Radiotherapy with or Without Cisplatin for p53 Mutated, Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN), ECOG-ACRIN-EA3132
 

Laryngology


Brad deSilva, MD
– Voice Outcomes Following Transcutaneous Steroid Injection for Vocal Fold Nodules Combined with Voice Therapy Compared to Voice Therapy Alone
 
Laura Matrka, MD – Treatment Alternatives in Adult Rare Disease; Assessment of Options in Idiopathic Subglottic Stenosis North American Airway Collaborative PR-02 Study (NoAAC PR-02 Study)
 
Laura Matrka, MD – Treatment of Vocal Cord Granulomas with Potassium Titanyl Phosphate (KTP) Laser vs. Traditional Proton-Pump Inhibitors (PPIs) 
 

Otology, Neurotology and Cranial Base Surgery


Oliver Adunka, MD
– A Proposal to Evaluate Revised Indications for Cochlear Implant Candidacy for the Adult CMS Population (co-investigators – Ed Dodson, MD and Aaron Moberly, MD)
 
Oliver Adunka, MD – Clinical Evaluation of the Cochlear Nucleus® CI532 Cochlear Implant in Adults (co-investigators – Ed Dodson, MD and Aaron Moberly, MD)
 
Oliver Adunka, MD – Cochlear Implantation during Vestibular Schwannoma Removal or During Labyrinthectomy Surgery for Treatment of Meniere’s Disease (co-investigators – Ed Dodson, MD and Aaron Moberly, MD) – hasn't started yet but expect IRB approval within the next month

Aaron Moberly, MD – Aural Rehabilitation for Adults Receiving Cochlear Implants
 
Aaron Moberly, MD – Aural Rehabilitation for Experienced Cochlear Implant Users
 

Rhinology


Brad Otto, MD
– A Prospective, Non-Randomized Study to Evaluate Treatment Outcome of Nasal Airway Obstruction Using the Aerin Medical Vivaerä Stylus (co-investigators – Alex Farag, MD and Kai Zhao, PhD)

Clinical Trials at the James Cancer Center