Early diagnosis through imaging technologiesMagnetic Resonance Elastography (MRE) is a noninvasive clinical diagnostic tool to uniquely assess tissue fibrosis of the liver. MRE is superior to many invasive techniques (i.e., biopsies, mechanical testing) because it can be performed in-vivo under physiologic conditions.
MRE has the ability to make tissue-stiffness measurements widely available and could revolutionize the diagnosis, monitoring and treatment of numerous diseases altering the stiffness of soft tissues. For example:
- Liver (hepatic fibrosis, non-alcoholic fatty liver disease, benign or malignant tumors)
- Pancreas (cancer)
- Heart (diastolic dysfunction, myocardial infarction, hypertrophic cardiomyopathy)
- Aorta (aneurysm, hypertension)
- Lungs (interstitial lung disease, COPD)
- Brain (multiple sclerosis, Alzheimer’s disease)
- Prostate (cancer)
- Breast (cancer)
Currently, the required tools (i.e., pulse sequences, MRE drivers, inversions) are being developed in this lab for the aforementioned applications in different organs. This lab is supported by grants from the NIH, AHA and other professional societies.
Past Students and Fellows