The Ohio State Wexner Medical Center is one of just 11 sites participating in an international, multicenter prospective randomized study to provide level I evidence for or against the single-dose versus 24-hour antibiotic. The study will include 8,000 primary total knee arthroplasty cases.
“We’re excited to be a part of this research to validate the safety and effectiveness of shorter-duration antibiotic treatment,” says Menghai Li, MD, PhD, director of the Division of Adult Reconstructive Surgery. “Infection in orthopaedic surgery is a dreaded complication. Our participation in the Perioperative Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty study will hopefully contribute to further lowering the SSI complication rate.”