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September 26, 2011

The Ohio State University’s Center for Personalized Health Care is gathering academic leaders, industry experts, government policymakers and healthcare providers from across the country to discuss the latest developments in P4 Medicine, which is a novel approach to individualized medical care that engages consumer participation, predicts and prevents disease, facilitates health, and creates a personalized life strategy wellness plan for each individual.

The Johanna and Ralph DeStefano Personalized Health Care National Conference will be held Oct. 6-7 at the Blackwell Inn, located at 2110 Tuttle Park Place, on the campus of The Ohio State University.

With a theme of “The Future of P4 Medicine and Its Impact on Clinical Care,” attendees will hear from experts about revolutionizing medicine and transforming healthcare delivery in a way which will result in more precise, cost-effective and higher quality health care for patients. Topics will focus on the infrastructure necessary to enable P4 Medicine, applications of genetics and genomics in clinical medicine, the latest breakthroughs in science, patient engagement and the barriers to making P4 Medicine a reality.

“We are leading the way in bringing P4 Medicine to our patients and consumers, and this year’s conference is focusing on its future and its impact on clinical care,” says Dr. Clay Marsh, executive director of OSU’s Center for Personalized Health Care. “Having visionaries and leaders like Johanna DeStefano support our national conference is a critical factor to bringing P4 Medicine to the community, to reduce costs and improve outcomes of healthcare delivery,” adds Marsh, who is also senior vice president for research in the Office of Health Sciences, and vice dean for research in the College of Medicine.

This year’s keynote speakers include William Dalton, MD, PhD, CEO and President, H. Lee Moffitt Cancer Center & Research Institute; Carlo Croce, MD, The John W. Wolfe Chair in Human Cancer Genetics, Professor and Chairman, Department of Molecular Virology, Immunology & Medical Genetics, The Ohio State University; Ralph Snyderman, MD, Director of the Center for Research on Prospective Health Care, James B. Duke Professor of Medicine, Chancellor Emeritus, Duke University; Ann Pendleton-Julian, PhD, Director, Architecture Section and Walter H. Kidd Professor, Austin E. Knowlton School of Architecture, The Ohio State University.

Leading as the conference’s first keynote speaker and discussing targeted cancer therapies, Dr. William Dalton is a cancer researcher who is interested in basic and translational research in molecular mechanisms of drug resistance and new drug discovery. He is an expert in health policy, with a specific interest in the study and development of effective approaches to cancer research, personalized cancer care and patient-centered research outcomes. In addition, he was the recipient of the 2010 Personalized Medicine Coalition’s National Leadership in Personalized Medicine (PMC) Award for his dedication to the development of personalized medicine.

The event’s second keynote speaker is Dr. Carlo Croce, a physician-scientist world-renowned for his contributions involving the genes and genetic mechanisms implicated in the pathogenesis of human cancer. Croce will present on the causes and consequences of microRNA dysregulation in cancer. His discoveries have led to revolutionary innovations in the development of novel and successful approaches to cancer prevention, diagnosis, monitoring and treatment, based on gene-target discovery, verification and rational drug development. 

Dr. Ralph Snyderman who developed Prospective Care, a novel approach to strategic health planning rather than reactive treatment of chronic disease, will discuss preventive medicine and healthcare reform. He is renowned for his contributions to the development of rational, effective and compassionate models of health care and is a recipient of many lifetime achievement awards for his dedication to the field of preventive and personalized medicine.

The final keynote address of the conference will be given by Ann Pendleton-Jullian, who will discuss complex and adaptive systems in health care and making the connections to patient engagement. Pendleton-Jullian is an internationally known architect, writer and educator whose work explores the interchange between architecture, landscape, culture, science and technology. She applies her design expertise to a wide range of complex problems and discussions around complexity, and much of her recent work focuses on empowerment and economic development through various projects.

Other speakers and expert panelis‚Äčts will discuss:

  • Novel approaches in the prediction and treatment of cancer
  • Advances in the prevention and treatment of cardiovascular disease
  • Community wellness
  • Creating a consumer-focused environment for participatory health care
  • Ohio as a center for healthcare reform, from a CEO’s perspective
  • P4 Medicine as a framework for value innovation (reducing cost and improving outcomes)

P4 Medicine focuses on creating systems to deliver medicine that focuses on executing key evidence-based practices to reduce healthcare costs and improve outcomes, and it embraces the interface between an individual’s unique DNA, environment and behavior to define their health and disease. P4 Medicine utilizes advances in genomics and molecular diagnostics discoveries to provide predictive information that is necessary to tailor, or personalize, disease management approaches for each individual. Therapeutics and health management tools are being developed to help prevent disease instead of merely treating the symptoms. Medicine of the future is also participatory. Patients will have access to a single portal that electronically stores their medical records and genetic profiles and tools that analyze these data to guide them to precise strategies to promote wellness. In addition, Marsh says that social networking and the power of games will be instrumental to engaging the consumer to taking ownership of their health care.


Contact: Sherri Kirk, Center for Personalized Health Care, 614-366-3277, or