Assistant Professor- Clinical
Department of Neurology
Division of Multiple Sclerosis and Neuroimmunology
460 W 12th Ave, 6th floor
Columbus, OH 43210
Cole.Harrington@osumc.edu
Research Interests
- Oligodendroglial biology and remyelination
- Oligodendroglial heterogeneity in inflammatory demyelinating models
- Impact of aging on oligodendroglial properties and remyelination
Current Research
Dr. Harrington’s research aims to understand how oligodendroglia function in the setting of an inflammatory environment and in aging with the goal of identifying pathways in multiple sclerosis that could be targeted to promote repair and remyelination.
Harrington lab Research publications
Research Techniques
- Experimental Autoimmune Encephalomyelitis animal models
- Demyelinating animal models
- T cell and oligodendroglial in vitro cell culture
- Flow cytometry
- Single-cell RNA sequencing
- RNAscope
- Immunohistochemistry
- Advanced microscopy
- Electron microscopy
- CRISPR gene editing
Education
- Postdoctoral Clinical and Research Fellowship: Neuroimmunology, Dr. Peter Calabresi and Dr. Dwight Bergles, Johns Hopkins University
- Clinical Training: Neurology residency, University of California San Francisco
- Graduate Training: Medical Scientist Training Program, University of California San Francisco