When you participate in a research study, you become a vital part of a team working to change the future of health care and improve lives.
The Ohio State Sports Medicine Research Institute is comprised of faculty from Orthopaedics, Family Medicine, Internal Medicine and Physical Therapy and colleagues in the College of Medicine, College of Veterinary Medicine, School of Health and Rehabilitation Sciences, Biomedical Informatics, Division of Cardiovascular Medicine and Division of Pulmonary, Allergy, Critical Care and Sleep Medicine. We collaborate extensively on research that is fully integrated with our clinical operations, leverages our partnership with the Ohio State Department of Athletics and is of benefit to the university.
If you have an interest in or question regarding our research projects, please contact SportsMedResearch@osumc.edu.
Evaluating ACL reconstruction success factors
Identifying athletes at risk for ACL injury
Outcomes of cartilage injuries
Tissue engineered cell-based repair product
Novocart® 3D is a cellular implant system where small amount of knee cartilage is removed in a an initial surgery, cleaned and "grown" on a 3-dimensional sponge-like scaffold and then implanted into the damaged area in a second surgery approximately 3 weeks later. This Phase 3 prospective, randomized, partially blinded multi-center study measures the safety and efficacy of Novocart compared to the current Microfracture standard of care in repairing articular cartilage defects of the knee.
Implant for joint surface lesions
This study compares the efficacy and safety of the Agili-C implant to the surgical standard of care treatment in patients suffering from joint surface lesions of the knee. Agili-C™ is a cell-free, off-the-shelf implant for use in cartilage and osteochondral defects in traumatic and osteoarthritic joints. The implant is a porous, biocompatible, and resorbable bi-phasic scaffold, consisting of interconnected natural inorganic calcium carbonate.A Treatment Study of Joint Surface Lesions of the Knee - Agili-C™ vs. Surgical Standard of Care
Regeneration of hyaline-like cartilage
This is a prospective, randomized trial designed to compare two treatments for articular cartilage defect legions: microfracture and Hyalofast® scaffold. Hyalofast is made from a synthetic form of a substance called hyaluronic acid that is found naturally in the knee joint and other places throughout the body. It is combined with autologous bone marrow aspirate concentrate and surgically implanted into the cartilage defect. It is believed that the bone marrow cells eventually will grow into new cartilage and fill the defect while the Hyalofast® eventually dissolves away with time.A Treatment Study for Damaged Knee Cartilage Requiring Repair--Hyalofast with BMAC
Dry Needling for "Runner's Knee"
This study is testing the effectiveness of "dry needling" for pain management and on muscle strength and leg function for those with knee pain. Dry needling consists of small, monofilament needles that are administered directly into the tissue and manipulated to make the muscle relax for pain relief. This technique is used to treat dysfunctions in skeletal muscle and connective tissue to help diminish pain, reduce impairments of body structure and restore function.
Subchondroplasty™ for Bone Marrow Lesions
This observational cohort follow-up study seeks to understand the post-operative outcomes of subjects choosing to undergo the Subchondroplasty™ (SCP™) procedure, a minimally invasive procedure to treat bone defects in the knee associated with bone marrow lesions (BMLs). BMLs are subchondral defects in the bone, also called insufficiency fractures. This follow-up study will collect information on the short- and long-term safety and effectiveness of the SCP procedure.
The Calypso Knee System is an investigational device designed to treat knee OA by absorbing excess load placed on your joint. OA usually affects the “inner side” of the knee, and the Calypso Knee System has been designed specifically to address this type of pain. Once implanted, the Calypso Knee System works like a shock absorber for your knee, designed to restore a more normal load balance within the joint.
The Calypso Knee System is implanted under the skin, alongside your knee joint, through a single incision. And unlike joint replacement procedures, none of your bone, ligament, or cartilage is removed, which may help maintain future treatment options.
Joint Health Assessment Study
First Time Patellar Dislocation
Knee Joint Bracing and Neuromuscular Training
Outcomes of surgical treatments for shoulder instability
This is an unblinded, multi-center, pragmatic randomized controlled clinical trial of operative versus non-operative treatments for atraumatic rotator cuff tears. A sample size of 700 patients will be enrolled with approximately equal numbers of patients randomized to operative treatment (surgery + post-op physical therapy) and non-operative treatment (physical therapy only without surgery). Both treatments are current standards of care.
Outcomes of shoulder surgery
Use of knee continuous passive motion (CPM) device after hip surgery
Continuous passive motion (CPM) devices are used to keep a joint in motion for extended periods of time and are thought to improve recovery by stimulating the healing of tissue and circulation of synovial fluid. This study evaluates the effectiveness of using a knee CPM device in the early post-operative period following an arthroscopic acetabular labral repair.