When you participate in a research study, you become a vital part of a team working to change the future of health care and improve lives.
Research study volunteers are essential in shaping the future of medicine. Whether it's a clinical trial of an experimental medication, a comparison of different treatments or a collection of data from people with a similar health condition or genetic background, community participants help researchers translate scientific discovery into lifesaving care. Many of our research studies are specific to knee, shoulder or hip medical procedures or conditions for which you may be a candidate.
If you have an interest in or question regarding our research projects, please browse our current studies below, contact ask your provider if you qualify or contact us at SportsMedResearch@osumc.edu.
Evaluating ACL reconstruction success factors
Identifying athletes at risk for ACL injury
Outcomes of cartilage injuries
Tissue engineered cell-based repair product
Novocart® 3D is a cellular implant system where small amount of knee cartilage is removed in a an initial surgery, cleaned and "grown" on a 3-dimensional sponge-like scaffold and then implanted into the damaged area in a second surgery approximately 3 weeks later. This Phase 3 prospective, randomized, partially blinded multi-center study measures the safety and efficacy of Novocart compared to the current Microfracture standard of care in repairing articular cartilage defects of the knee.
Implant for joint surface lesions
This study compares the efficacy and safety of the Agili-C implant to the surgical standard of care treatment in patients suffering from joint surface lesions of the knee. Agili-C™ is a cell-free, off-the-shelf implant for use in cartilage and osteochondral defects in traumatic and osteoarthritic joints. The implant is a porous, biocompatible, and resorbable bi-phasic scaffold, consisting of interconnected natural inorganic calcium carbonate.A Treatment Study of Joint Surface Lesions of the Knee - Agili-C™ vs. Surgical Standard of Care
Regeneration of hyaline-like cartilage
This is a prospective, randomized trial designed to compare two treatments for articular cartilage defect legions: microfracture and Hyalofast® scaffold. Hyalofast is made from a synthetic form of a substance called hyaluronic acid that is found naturally in the knee joint and other places throughout the body. It is combined with autologous bone marrow aspirate concentrate and surgically implanted into the cartilage defect. It is believed that the bone marrow cells eventually will grow into new cartilage and fill the defect while the Hyalofast® eventually dissolves away with time.A Treatment Study for Damaged Knee Cartilage Requiring Repair--Hyalofast with BMAC
Dry Needling for "Runner's Knee"
This study is testing the effectiveness of "dry needling" for pain management and on muscle strength and leg function for those with knee pain. Dry needling consists of small, monofilament needles that are administered directly into the tissue and manipulated to make the muscle relax for pain relief. This technique is used to treat dysfunctions in skeletal muscle and connective tissue to help diminish pain, reduce impairments of body structure and restore function.
Subchondroplasty™ for Bone Marrow Lesions
This observational cohort follow-up study seeks to understand the post-operative outcomes of subjects choosing to undergo the Subchondroplasty™ (SCP™) procedure, a minimally invasive procedure to treat bone defects in the knee associated with bone marrow lesions (BMLs). BMLs are subchondral defects in the bone, also called insufficiency fractures. This follow-up study will collect information on the short- and long-term safety and effectiveness of the SCP procedure.
The Calypso Knee System is an investigational device designed to treat knee OA by absorbing excess load placed on your joint. OA usually affects the “inner side” of the knee, and the Calypso Knee System has been designed specifically to address this type of pain. Once implanted, the Calypso Knee System works like a shock absorber for your knee, designed to restore a more normal load balance within the joint.
The Calypso Knee System is implanted under the skin, alongside your knee joint, through a single incision. And unlike joint replacement procedures, none of your bone, ligament, or cartilage is removed, which may help maintain future treatment options.
Joint Health Assessment Study
First Time Patellar Dislocation
Knee Joint Bracing and Neuromuscular Training
Outcomes of surgical treatments for shoulder instability
This is an unblinded, multi-center, pragmatic randomized controlled clinical trial of operative versus non-operative treatments for atraumatic rotator cuff tears. A sample size of 700 patients will be enrolled with approximately equal numbers of patients randomized to operative treatment (surgery + post-op physical therapy) and non-operative treatment (physical therapy only without surgery). Both treatments are current standards of care.
Outcomes of shoulder surgery
Hip Treatment Outcomes
Interdisciplinary Approach for Hip Pain
The purpose of this study is to better understand whether or not interdisciplinary care can impact treatment decisions and outcomes for patients with non-arthritic hip pain. Patients who participate will be placed in 1 of 2 groups: they will either receive 1) their standard evaluation with a hip surgeon or 2) their standard evaluation with a hip surgeon followed by a brief assessment with a physical therapist. Both groups will have the opportunity to continue onto a treatment trial in which they may receive 3 weeks of physical therapy focused on posture and movement.
Subchondroplasty™ for bone marrow lesions in the hip
Treatment for Greater Trochanteric Pain Syndrome (Lateral Hip Pain)
The purpose of this study is to compare the effects of two different physical therapy programs on pain and function in individuals diagnosed with greater trochanteric pain syndrome (GTPS) (also known as lateral hip pain). Patients who participate will receive instruction from a physical therapist regarding 1 of 2 exercise programs to complete over a 4-week period at home.Treatment for Greater Trochanteric Pain Syndrome