Lab
Pavilion 1st Floor Suite 1B
Columbus, OH 43221
Physician, Assistant Professor
Neurology
Department: Neurology
I am a neurologist with subspecialty training in multiple sclerosis and related neuro-immunological disorders of the central nervous system. I chose this specialization because MS affects everyone differently and changes with age. It’s a privilege to use my skills to help improve my patients’ lives.
In my practice, I enjoy getting to know each patient. I’m passionate about finding the best treatment strategies possible depending on each patient’s unique needs and disease characteristics.
My research is focused on aging and MS, specifically how clinical and molecular changes related to aging affect disease progression. The goal of my research is to use evidence-based treatment strategies, incorporated with an individual’s aging biology, to improve care for people with MS and optimize their quality of life.
I enjoy spending my free time with my family and building custom Lego creations.
Please note: Not all physicians schedule patients at each listed location.
I graduated from medical school at the University of Texas Southwestern Medical Center, where I stayed for my neurology residency and received the Fred Baskin Young Investigator Award for my research on the efficacy of MS disease-modifying therapies with age. I finished a 2-year fellowship in MS at Mount Sinai, which was funded by the Sylvia Lawry Physician Fellowship grant. During fellowship, I also earned a Masters in Clinical Research before joining OSU in 2021.
My NIH-funded research at OSU seeks to understand mechanisms of biological aging in MS as reflected by biomarkers of senescence and epigenetic alterations and their associations with MS disease outcomes. I am also interested in distinguishing age-related changes from MS-related disease progression in older adults with MS. My goal is to develop novel therapeutics and treatment strategies for patients by taking into consideration a person’s unique aging biology to mitigate disability and functional decline in MS and related disorders.

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At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the University requires annual disclosures from all faculty members with external interests related to their University responsibilities.
As of 11/3/2025, Yinan Zhang has reported no relationships with companies or entities.