Mark Wewers

Mark Wewers, MD

  • Pulmonary Disease
  • Critical Care Medicine
  • Physician
4.9 out of 5
  • 30 Patient Satisfaction Ratings
  • 16 Patient Comments

Insurances We Accept


About Me

As a pulmonary care specialist, I have a long-standing interest in diagnosing and treating patients who suffer from lung ailments. My focus is to help patients understand their disease, as knowledge promotes better adherence to treatments and helps in symptom management.

Specifically, I am passionate about alpha 1-antitrypsin (AAT) deficiency. This rare condition exists in individuals who do not produce enough AAT to protect the lungs from emphysema. I head the local Alpha-1 Research Registry, which supports patients with this condition.

In addition to my clinical work, I am a member of the Molecular Carcinogenesis and Chemoprevention Program at the OSUCCC – James, where my research focuses on host defense against pathogens. I seek to understand how the lung and circulating mononuclear phagocytes sense danger from pathogens and respond with robust inflammation around IL-1.

My recent studies address the important role of the inflammasome adaptor ASC as a contributor to lung airway inflammation, as well as the regulation of the pyroptosis-generating inflammasome mediator gasdermin D as a factor in lung cell survival.

The Ohio State University Wexner Medical Center brings together the best physicians in primary and specialty care. With so many expert colleagues on our team, I always know where to turn for difficult questions.
  • Rated in the top 10 percent of physicians in the nation for patient satisfaction, 2015
  • Headed first commercial alpha 1-antitrypsin (AAT) infusion study, now standard of care
  • Research lab funded for over 25 years to study mechanisms to protect the lung
  • Training and working with MD and PhD students in my laboratory for three decades
  • Best Doctor in America 2017

Procedures and Conditions I Treat

  • Asthma
  • Sleep Disorders
  • Pulmonary Medicine
  • Pulmonary Disease, Chronic Obstructive
  • Respiratory Insufficiency
  • Respiration Disorders
  • Pulmonary Emphysema

Locations Where I Practice

Please note: Not all physicians schedule patients at each listed location. Please call the “Schedule an appointment” number shown above for scheduling assistance.

Education and Training

Education History

Medical School

Univ. of Arkansas, Little Rock, AR
9/1/1972 - 6/1/1976


University of Arkansas College of Medicine, Little Rock, AR

7/1/1976 - 6/30/1977


Univ. of Arkansas, Little Rock, AR

7/1/1977 - 6/30/1979


Univ. of Arkansas, Little Rock, AR

7/1/1979 - 6/30/1981

Board Certifications

American Board of Internal Medicine

American Board of Internal Medicine (Subspecialty: Pulmonary Disease)

American Board of Internal Medicine (Subspecialty: Critical Care Medicine)

Academic Information

My Department

Internal Medicine

My Division

Pulmonary, Allergy, Critical Care and Sleep Medicine

More About My Work


The overall patient satisfaction rating is an average of all patient responses to the six doctor communication related questions shown below from the Clinician and Group Consumer Assessment of Healthcare Providers and Systems survey. For additional information about the patient satisfaction survey, please visit our Patient Satisfaction Survey page.

The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of Ohio State Wexner Medical Center.

30 Patient Satisfaction Reviews

  • Overall
    4.9 out of 5
  • Explains Things Clearly
    4.9 out of 5
  • Listens Carefully
    4.9 out of 5
  • Gives Understandable Instructions
    4.9 out of 5
  • Knows My Medical History
    4.8 out of 5
  • Shows Respect
    4.9 out of 5
  • Time Spent Together
    4.9 out of 5
  • Reviewed on Oct 16, 2020

    Dr Wewers is the best doctor I have ever seen

  • Reviewed on Oct 09, 2020

    Dr. Wewers was extremely knowledgeable and helpful with all my questions.

  • Reviewed on Sep 10, 2020

    He is the best. Everything is great with him.

  • Reviewed on Aug 11, 2020

    I was disappointed that all of the documents (i.e., test results, image reports etc.) that were requested by Dr. Wewers office to be sent there in advance of my appointment had never been reviewed. I spent $30.00 sending them overnight delivery so that they would have been received a week in advance of my appointment. But no one seemed to have them or had looked at them. Fortunately, I had copies of everything I had sent with me at my appointment.l It doesn't make sense to require these documents in advance if no one pays any attention to them -

  • Reviewed on Apr 16, 2020

    I liked that I was a telephone appointment during the COVID-19 pandemic. He answered many of my concerns about COVID-19 as it related to my high risk condition -

  • Reviewed on Mar 04, 2020

    Both Dr. Wewers and his assistant spent individual and together time with me. They discussed my case together in front of me and my daughter so we could understand what could be happening with me and how they want to investigate it. They did not rush, but took time with me and listened caringly, It was a super visit!

  • Reviewed on Feb 26, 2020


  • Reviewed on Dec 27, 2019

    Dr. Wewers took extra time to go over years of test and show me how much I've improved.

  • Reviewed on Oct 22, 2019

    Always attentive & supportive.

  • Reviewed on Sep 12, 2019

    All good!

Load More Comments

Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the University requires annual disclosures from all faculty members with external interests related to their University responsibilities.

As of 11/01/2020, Dr. Wewers has reported no relationships with companies or entities.