Physician, Assistant Professor
Urology
Department: Urology
I’m a urologist who specializes in treating patients with complex kidney stones and enlarged prostates. I have specialty training performing holmium laser enucleation of the prostate (HoLEP) and percutaneous nephrolithotomy (PCNL) procedures.
I’m passionate about using my skills to reduce a patient’s suffering and help improve their quality of life. It’s rewarding when I can successfully remove a kidney stone that was causing a patient excruciating pain or threatening kidney function. Similarly, it’s gratifying when a patient has a successful HoLEP and can urinate on their own again after living with a catheter for months or years.
The Ohio State University Wexner Medical Center has a thriving Endourology division, providing cutting-edge care for patients. I’m honored to be part of this team and to help bring HoLEP to the people of Columbus and beyond. As someone who’s benefited from the mentorship of others, I’m also excited to pay it forward and work with medical students and residents here at Ohio State.
My research interests include enhancing our understanding of stone pathogenesis and helping to develop strategies to improve surgical outcomes. The opioid epidemic is another of my research areas. One of my peer-reviewed publications revealed that efforts to reduce opioid prescriptions after ureteroscopy resulted in lower rates of new persistent opioid use. I’m also a reviewer for publications including European Urology Focus, Journal of Endourology and Urology.
In my free time, my wife and I like cooking new recipes, grilling and sampling bourbon and craft beers. I also enjoy exercising, especially swimming, as I was a varsity swimmer for four years.
Please note: Not all physicians schedule patients at each listed location.
My research interests are in benign prostatic hyperplasia and kidney stones, comparative effectiveness of new surgical technologies, and health services research methods for kidney stones and benign prostatic hyperplasia. I am involved in work for improving medical stone management, of understanding the side effects of medications used for kidney stone prevention, and of understanding what factors influence a man's choice to undergo surgery for an enlarged prostate.
I am also a reviewer for publications including European Urology Focus, the Journal of Endourology and Urology.
I appreciate the commitment to innovation here in The Ohio State University College of Medicine, and the readily available resources that allow me to pursue highly complex research.
The overall patient satisfaction rating is an average of all patient responses to the six doctor communication related questions shown below from the Clinician and Group Consumer Assessment of Healthcare Providers and Systems survey. For additional information about the patient satisfaction survey, please visit our Patient Satisfaction Survey page.
The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of Ohio State Wexner Medical Center.
At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the University requires annual disclosures from all faculty members with external interests related to their University responsibilities.
As of 11/3/2025, Matthew Lee has reported no relationships with companies or entities.
Knowledgeable and
Professional, compassionate, very engaged
One of best doctors I've ever had
Wonderful provider excellent care
Good
Everything was great
AOK
Knowledgeable about my condition and very concerned about answering any and all questions regarding my condition and the anticipated procedure.
My provider explains. Everything very thourghly and answers my questions
Good
Very kind and respectful
Very kind, encouraging and informative
5 star. I could not ask for more.I feel so much better.
Good
Everything was excellent.
Very courteous, concerned, knowledgeable, gave me time to ask questions and addressed all my questions. Discussed treatment plan, possible issues, side effects and recovery.
Read a lot about him and was very impressed
Real good real good
Very good. Very easy to discuss my situation.
Dr. Lee is very kind and courteous. I have complete confidence in him.