Sofia Lesica, PhD
Physician, Assistant Professor
Clinical Neuropsychology
Make an appointment
614-293-4969Conditions and expertise
- Epilepsy
- Mild Cognitive Impairment
- Dementia
- Alzheimer's Disease
- Neuro-Oncology
- Stroke
Locations
- Center for Neuromodulation in Davis Outpatient Care
- Neurology in Martha Morehouse Outpatient Care
- Lab in Martha Morehouse Outpatient Care
Academics and research
Department: Neurology
About
- Gender
- Female
- Additional languages
- Italian
Biography
I am a clinical neuropsychologist at The Ohio State University Wexner Medical Center. I specialize in the assessment of cognitive and behavioral changes associated with neurological conditions, including epilepsy. My practice focuses on comprehensive neuropsychological evaluation and neuropsychological rehabilitation to support accurate diagnosis and personalized treatment planning.
I conduct neuropsychological assessments for individuals with a wide variety of neurological conditions, with specialized expertise in evaluating patients with epilepsy, including those being considered for epilepsy surgery. Neuropsychological assessment results help guide differential diagnosis and inform treatment planning as part of a multidisciplinary care approach.
My primary focus is on improving my patients' quality of life. I tailor each evaluation to the unique needs, experiences and background of the individual, and provide recommendations designed to address their questions and concerns. This includes practical strategies to help patients manage and compensate for cognitive difficulties in their daily lives.
My practice is grounded in evidence-based care and ongoing research. By staying current with new developments in neuropsychology, I strive to provide patients with the most informed assessments, recommendations and support possible.
Conditions and expertise
- Alzheimer's Disease
- Delirium, Dementia, Amnestic, Cognitive Disorders
- Dementia
- Epilepsy
- Frontotemporal Dementia
- Memory Disorders
- Mild Cognitive Impairment
- Neuro-Oncology
- Stroke
Locations
Please note: Not all physicians schedule patients at each listed location.
Credentials
Education
- Fellowship - Clinical Neuropsychology
- Cleveland Clinic Graduate Medical Education, Cleveland, OH
9/1/2024 - 8/28/2026 - Internship - Clinical Health Psychology
- Long Island Jewish Medical Center, New Hyde Park, NY, United States
7/20/2023 - 6/30/2024 - Doctor of Philosophy
- Central Michigan University, Mount Pleasant, MI, United States
8/16/2019 - 6/20/2024
Academics and research
I am a researcher whose work focuses on cognition in epilepsy and on the factors that influence cognitive and functional outcomes for people living with neurological disorders. I specialize in neuropsychological assessment, cognitive phenotyping and rehabilitation research, using quantitative, mixed-method and real-world data approaches to better understand brain-behavior relationships.
My research is centered on improving the understanding, evaluation and treatment of cognitive changes associated with epilepsy. I study how neurological conditions affect thinking, memory and everyday functioning, with a particular interest in developing and refining methods for cognitive phenotyping and neuropsychological assessment. These efforts help advance our ability to identify meaningful cognitive patterns and support more personalized approaches to care and intervention.
A significant area of my work examines cognitive and functional outcomes in individuals with epilepsy, including those undergoing epilepsy surgery. Through this research, I aim to better understand the factors associated with cognitive change over time and to generate evidence that informs clinical decision-making and patient-centered treatment planning.
I am also interested in cognitive rehabilitation and the development of strategies that promote long-term quality of life and functional independence. By integrating neuropsychological assessment with real-world data and quantitative research methods, I seek to translate research findings into practical applications that can improve outcomes for individuals affected by epilepsy and related neurological conditions.
My ongoing and future research goals include advancing cognitive phenotyping techniques, improving assessment tools, evaluating rehabilitation interventions and expanding knowledge of the cognitive and functional effects of epilepsy across diverse patient populations. Through this work, I hope to contribute to more precise, evidence-based approaches for understanding and addressing cognitive health in epilepsy.
Research interests
- Cognition
- Epilepsy
- Neuropsychological Assessment
- Rehabilitation
- Functional Outcomes
- Ccognitive Phenotypes
Academic information
- Department:
- Neurology
- Division:
- Neurology
More about my research
Consulting and related relationships
At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the University requires annual disclosures from all faculty members with external interests related to their University responsibilities.
As of 11/3/2025, Sofia Lesica has reported no relationships with companies or entities.