Assistant Clinical Professor

College of Medicine
Department of Neurological Surgery

Andrew.Grossbach@osumc.edu

Research Interests

  • Spinal biomechanics
  • Spinal outcomes measures
  • Effects of exercise and brain derived neurotrophic factor (BDNF) on neural connectivity, neural function and neural recovery in the human brain and spinal cord
  • Transcriptome analysis of human epilepsy 
  • Mitochondrial DNA analysis of human epilepsy

 Clinical Interests

  • Complex adult spinal deformity/reconstructive spinal surgery
  • Minimally invasive spinal surgery
  • Degenerative spinal disorders
  • Spine Navigation
  • Spine and head trauma
  • Spinal tumors
  • General neurosurgery

Enrolling Clinical Trials

  • Spinal Cord Injury Neuroprotection with Glyburide - NCT02524379
  • Multicenter Study to Assess the Efficacy and Safety of VX-210 in Subjects with Acute Traumatic Cervical Spinal Cord Injury - NCT02669849
  • Multicenter, Prospective, Single Arm Study of Patients Undergoing a Two or Three Level ACDF Using ViviGen® Cellular Bone Matrix in Conjunction with Cervical Allograft Spacers and DePuy Synthes Spine Anterior Cervical Plate Systems - NCT02814825
  • Prospective Multicenter Follow-up of Patients Undergoing Instrumented Thoracic and Lumbar Arthrodesis Supplemented by the Implanet Jazz SystemTM - NCT02411799
  • Prospective Follow-up of Elderly Patients Undergoing Instrumented Lumbar Arthrodesis Supplemented by the Implanet Jazz System 
  • Radiographic and Clinical Outcomes Following Unilateral or Bilateral Posterior Fixation in Minimally Invasive Transforaminal Lumbar Interbody Fusions - NCT01996371
  • Spinal Arthrodesis and Spinal Arthroplasty Database - NCT01979094

Education
BA: Hamline University
MD: University of Minnesota Medical School

Postgraduate Training
Residency: Department of Neurosurgery, University of Iowa Hospitals and Clinics
Fellowship: Complex reconstructive and minimally invasive spine, Rush University Medical Center
Fellow associate: University of Iowa Hospitals and Clinics

Recent Publications
  • Grossbach, AJ, Mahaney, KB, Menezes, AH. Pediatric meningiomas: 65-year experience at a single institution. J Neurosurg Pediatr. 2017;20 (1):42-50. doi: 10.3171/2017.2.PEDS16497. PubMed PMID:28474981 .

  • Yang, J, Bassuk, AG, Merl-Pham, J, Hsu, CW, Colgan, DF, Li, X et al.. Catenin delta-1 (CTNND1) phosphorylation controls the mesenchymal to epithelial transition in astrocytic tumors. Hum. Mol. Genet. 2016;25 (19):4201-4210. doi: 10.1093/hmg/ddw253. PubMed PMID:27516388 PubMed Central PMC5291196.

  • Hitchon, PW, Abode-Iyamah, K, Dahdaleh, NS, Grossbach, AJ, El Tecle, NE, Noeller, J et al.. Risk factors and outcomes in thoracic stenosis with myelopathy: A single center experience. Clin Neurol Neurosurg. 2016;147 :84-9. doi: 10.1016/j.clineuro.2016.05.029. PubMed PMID:27310291.

  • Erwood, AM, Abel, TJ, Grossbach, AJ, Ahmed, R, Dahdaleh, NS, Dlouhy, BJ et al.. Acutely unstable cervical spine injury with normal CT scan findings: MRI detects ligamentous injury. J Clin Neurosci. 2016;24 :165-7. doi: 10.1016/j.jocn.2015.09.004. PubMed PMID:26601812.

  • Abode-Iyamah, KO, Stoner, KE, Grossbach, AJ, Viljoen, SV, McHenry, CL, Petrie, MA et al.. Effects of brain derived neurotrophic factor Val66Met polymorphism in patients with cervical spondylotic myelopathy. J Clin Neurosci. 2016;24 :117-21. doi: 10.1016/j.jocn.2015.07.016. PubMed PMID:26461908.

  • Grossbach, AJ, Viljoen, SV, Hitchon, PW, DeVries Watson, NA, Grosland, NM, Torner, J et al.. Vertebroplasty plus short segment pedicle screw fixation in a burst fracture model in cadaveric spines. J Clin Neurosci. 2015;22 (5):883-8. doi: 10.1016/j.jocn.2014.11.031. PubMed PMID:25769251.

  • Abel, TJ, Dalm, BD, Grossbach, AJ, Jackson, AW, Thomsen, T, Greenlee, JD et al.. Lateralized effect of pallidal stimulation on self-mutilation in Lesch-Nyhan disease. J Neurosurg Pediatr. 2014;14 (6):594-7. doi: 10.3171/2014.8.PEDS1451. PubMed PMID:25303157.

  • Grossbach, AJ, Abel, TJ, Smietana, J, Dahdaleh, N, Severson, MA 3rd, Hasan, D et al.. Impalement brain injury from steel rod causing injury to jugular bulb: case report and review of the literature. Brain Inj. 2014;28 (12):1617-21. doi: 10.3109/02699052.2014.934284. PubMed PMID:25019335.

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