Ernest Mazzaferri, MD

Physician, Professor

Interventional Cardiology

Make an appointment

614-293-7677
Accepting new patients

Conditions and expertise

  • High Blood Pressure
  • Hypercholesterolemia
  • Heart Valve Diseases
  • Coronary Care Units
  • Coronary Artery Disease
  • Coronary Balloon Angioplasty

View all conditions

Locations

  • Outpatient Care Upper Arlington

View location details

Academics and research

Department: Internal Medicine

View my research

About

Gender
Male

Biography

As an interventional cardiologist, I specialize in complex coronary artery disease, valve disorders and chronic total occlusions of coronaries. I believe that medical care should be a team effort among the physician, medical staff, family and most importantly, the patient. I strive to provide individualized care that’s tailored specifically to my patients’ needs and do my best to simplify complex problems so they can make informed decisions about treatment plans. I’m motivated to positively influence the health and lives of others.

In my free time, I enjoy spending time with my family and traveling.

Highlights

  • Induction into the Gold Humanism Honor Society, 2018
  • Medical Director, The Richard M. Ross Heart Hospital
  • Charles A. Bush Professor of Cardiovascular Medicine
  • Rated in the top 10 percent of physicians in the nation for patient satisfaction, 2014-2019
  • Named to Castle Connolly's Regional Top Doctors list
  • Courage to Teach Award, The Ohio State University College of Medicine, 2018
  • Best Doctor in America, 2017

Conditions and expertise

  • Acute Coronary Syndrome
  • Cardiovascular Diseases
  • Coronary Artery Disease
  • Coronary Balloon Angioplasty
  • Coronary Care Units
  • Heart Attack
  • Heart Catheterization
  • Heart Valve Diseases
  • High Blood Pressure
  • Hypercholesterolemia
  • Internal Medicine
  • Percutaneous Coronary Intervention

Locations

Please note: Not all physicians schedule patients at each listed location.

Credentials

Education

Fellowship - Interventional Cardiology
Ohio State University Wexner Medical Center, Columbus, OH, United States
7/1/2005 - 6/30/2006
Fellowship - Cardiovascular Disease
University of Florida Medical School, Gainesville, FL
7/1/2002 - 6/30/2005
Residency - Internal Medicine
Ohio State University Wexner Medical Center, Columbus, OH, United States
7/1/1999 - 6/30/2002
Doctor of Medicine (MD)
Ohio State University College of Medicine, Columbus, OH, United States
9/1/1995 - 6/30/1999

Certifications

  • American Heart Association National Center
    9/16/2025
  • American Board of Internal Medicine/Interventional Cardiology
    11/9/2006
  • American Board of Internal Medicine/Cardiovascular Disease
    11/7/2005

Academics and research

It’s exciting being part of such a great university and academic medical center, and I appreciate the opportunity to work with many talented colleagues and providers at Ohio State. I also enjoy participating in clinical trials as well as teaching and mentoring the physicians of the future. My primary research interest is translational research that explores unique family genetics of early onset coronary artery disease.

Research interests

  • Early Onset Coronary Artery Disease

Academic information

Department:
Internal Medicine
Division:
Cardiovascular Medicine

More about my research

Ratings and reviews

The overall patient satisfaction rating is an average of all patient responses to the six doctor communication related questions shown below from the Clinician and Group Consumer Assessment of Healthcare Providers and Systems survey. For additional information about the patient satisfaction survey, please visit our Patient Satisfaction Survey page.

The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of Ohio State Wexner Medical Center.

218 Patient Satisfaction Reviews

4.9 out of 5 overall
  • Explains Things Carefully
    4.9 / 5
  • Listens Carefully
    4.9 / 5
  • Gives Understandable Instructions
    4.9 / 5
  • Knows My Medical History
    4.9 / 5
  • Shows Respect
    5.0 / 5
  • Time Spent Together
    4.9 / 5

Patient Comments

  • Reviewed on Dec 10, 2025

    Good

  • Reviewed on Dec 08, 2025

    He listens and explains everything very well. Down to earth and easy to talk with.

  • Reviewed on Dec 08, 2025

    Excellent team

  • Reviewed on Nov 27, 2025

    overall, you could tell that he cared for you as a person

  • Reviewed on Nov 26, 2025

    Thoughtful analytical concerned with my wellbeing!

Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the University requires annual disclosures from all faculty members with external interests related to their University responsibilities.

As of 11/3/2025, Dr. Mazzaferri has reported no relationships with companies or entities.

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