Heart and Vascular
2nd Floor East
Columbus, OH 43221
Physician, Professor
Interventional Cardiology
Department: Internal Medicine
As an interventional cardiologist, I specialize in complex coronary artery disease, valve disorders and chronic total occlusions of coronaries. I believe that medical care should be a team effort among the physician, medical staff, family and most importantly, the patient. I strive to provide individualized care that’s tailored specifically to my patients’ needs and do my best to simplify complex problems so they can make informed decisions about treatment plans. I’m motivated to positively influence the health and lives of others.
In my free time, I enjoy spending time with my family and traveling.
Please note: Not all physicians schedule patients at each listed location.
It’s exciting being part of such a great university and academic medical center, and I appreciate the opportunity to work with many talented colleagues and providers at Ohio State. I also enjoy participating in clinical trials as well as teaching and mentoring the physicians of the future. My primary research interest is translational research that explores unique family genetics of early onset coronary artery disease.

The overall patient satisfaction rating is an average of all patient responses to the six doctor communication related questions shown below from the Clinician and Group Consumer Assessment of Healthcare Providers and Systems survey. For additional information about the patient satisfaction survey, please visit our Patient Satisfaction Survey page.
The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of Ohio State Wexner Medical Center.
At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the University requires annual disclosures from all faculty members with external interests related to their University responsibilities.
As of 11/3/2025, Ernest Mazzaferri has reported no relationships with companies or entities.
Tries to be open minded but clearly does not understand my point of view. Allopathic medicine has to deal with those of us who believe in alternative care and madness
All good
Excellent
Good
Excellent team
He listens and explains everything very well. Down to earth and easy to talk with.
The usual thorough exam and friendly discussion of my heart health
He was excellent in all ways. Cared about me and my health and about whether I understood all that he said.
Caring and thorough.
Dr.Maxzeferri is outstanding!
Dr Mazz is always great. Listens and suggests ways to keep you in good health
Exceptional
Excellent Doctor very interested in all of my health concerns.
Very professional yet very caring. Demonstrated a genuine interest in me and my health.
Dr is the best. I trust him explicitly. Great communicator and very empathetic . I
He has a very friendly patient/doctor manner
I am extremely happy With Dr Mazzaferri, he is a kind and patient professional, very attentive and even a great sense of humor! Always feel safe with him taking care of my heart! Thank you Dr M!
He made me feel well cared for. He provided information and showed respect. He's a 10 plus!
He was excellent. Easy to talk to and explained things very well.
Dr Mazz is the ultimate professional. He cares for his patients and presents the hard truth when necessary in an understandable way.