Parkinson’s disease (PD) is usually not diagnosed until after age 60 because symptoms don’t appear until more than 50% of the nerve cells that produce dopamine in the brain are destroyed. The symptoms usually begin quite gradually, often on only one side of the body. As the disease progresses, it usually moves to both sides.

Common symptoms of PD involve motor skills

An expert in Parkinson's disease tests the muscle and reflexes of a patient.

An expert in Parkinson's disease will conduct an exam evaluating a person's movement and muscle tone. Those with Parkinson’s disease may have:

  • Tremor 
  • Involuntary twisting in your torso, arms, legs, or face (called dyskinesia)
  • Rigidity or stiffness in your neck, arms or legs
  • Slowness of movement (called bradykinesia)
  • Poor balance and coordination

Not every person with PD develops the same symptoms.

Other symptoms may include trouble chewing or swallowing. Often, your voice may weaken, and you may not be able to create variations in volume or emotion, making you sound monotone.

Because PD is a movement disorder, many people are unaware of additional non-motor symptoms that often occur with the disease, including:

  • Cognitive changes – problems with thinking, word finding and judgment
  • Depression and anxiety
  • A loss of smell or reduced sensitivity to odors
  • Vision problems
  • Fatigue
  • Constipation
  • Lightheadedness
  • Hallucinations and/or delusions
  • Changes in sex drive or impotence
  • Sleep problems – difficulty falling or staying asleep or vivid dreams
  • Excessive sweating, drooling
  • Urinary issues – frequency, urgency or problems emptying the bladder
  • Constipation

As symptoms worsen, simple tasks can become more difficult, making PD a frustrating disease. This is exactly why The Center for Parkinson's Disease and Other Movement Disorders has experts from so many different medical specialties to ensure your best possible physical and mental health.

How is Parkinson’s disease diagnosed?

Diagnosing Parkinson’s disease is sometimes difficult, since early signs may mimic other movement disorders or other diseases and there is no blood or laboratory test for PD.

Before making a diagnosis, your doctor will discuss your health, medical and family history and conduct a complete physical and neurological exam. Most people develop PD due to an interaction between genetics and environment. In some cases, PD symptoms are triggered by certain drugs or related to structural abnormalities in the brain, so you doctor will want to know about all of your medications, as well as review any brain imaging.

If not Parkinson’s disease, could it be a different movement disorder?

Patient getting an MRIImaging studies, such as a computed tomography (CT) scan, magnetic resonance imaging (MRI) or a dopamine transporter SPECT scan (DaTscan), may be used to rule out other disorders with similar symptoms.

Learn more about Parkinson's disease

Meet our specialists

Ariane Park, MD, MPH

Ariane Park, MD, MPH

Co-director of The Center for Parkinson's Disease and Other Movement Disorders

Dr. Park manages care for patients with all types of movement disorders, including Parkinson’s disease, tremor and dystonia.

Clinical profile

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Pietro Mazzoni, MD

Neurologist

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Zachary Jordan, MD

Neurologist

Brian Dalm, MD

Brian Dalm, MD

Dr. Dalm is a neurosurgeon specializing in pain and functional neurosurgical disorders. His work includes research into the benefits of neuromodulation therapy for a patient.

 Clinical profile

Clarisse Goas, MS, CNP

Clarisse Goas, MS, CNP

Goas specializes in movement disorders and has experience in clinical trials, including new medication symptomatic interventions, deep brain stimulation and intestinal pump drug delivery systems.

Clinical profile

DavisRozena

Rozena Davis, MS, CNP

Davis is part of the clinical trials team and has experience with advanced therapies, such as deep brain stimulation for a variety of movement disorders, including Parkinson’s disease, dystonia and tremor disorders.

Clinical profile

Jessica Truelove, MS, CNP

Jessica Truelove, MS, CNP

Truelove has specialized training in both cognitive disorders and movement disorders and is part of the research team in both neurology divisions.

Clinical profile

Katherine Ambrogi, BSN, RN

Katherine Ambrogi, BSN, RN

Ambrogi serves as the clinical research manager movement disorders, specifically Parkinson's disease and other tremor disorders. In coordination with the Center for Clinical Research Management, she coordinates, plans, develops and implements clinical protocols in accordance with research parameters set by the principle investigator.

Victoria Miller

Victoria Miller

Clinical Research Coordinator

Jonathan Zins

Jonathan Zins, DPT, PT

Dr. Zins is the Parkinson’s disease team coordinator in outpatient rehabilitation. He is a board-certified neurologic clinical specialist, treating patients with a variety of neurologic injury and disease.

Academic profile

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Sarah Grim, LISW

Grim, as a social worker, provides support for our patients and their caregivers. She shares information on community resources, long-term care and home health, Medicare and Medicaid, work-related issues and more.

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Victoria Klee, LGC

As a genetic counselor, Klee helps patients understand their family medical history, identify the best genetic test for their movement disorder and help explain their treatment options, including gene-targeting therapies. Klee manages our Parkinson's disease GENEration study.

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