NAEC Level 4 Epilepsy CenterThe Comprehensive Epilepsy Center provides patients the highest standard of care, offering proven therapies delivered by a team of experts collaborating through Ohio State’s Neurological Institute. The center includes physicians board-certified in epilepsy, clinical neurophysiology, or both, full-time EEG technologists, a dedicated epilepsy nurse practitioner, and a pharmacist specializing in epilepsy drug treatments.

The Ohio State University Wexner Medical Center is a Level 4 Epilepsy Center, the highest rating of the National Association of Epilepsy Centers. Our industry-leading, eight-bed Epilepsy Monitoring Unit allows our team to closely evaluate episodes of loss of consciousness or diagnostically challenging seizures. By pinpointing areas of the brain where the seizures originate, we’re able to reveal a range of potential solutions.

Diagnostic tests available at the Comprehensive Epilepsy Center include:

  • Electroencephalogram (EEG)
  • Continuous video-EEG monitoring (V-EEG)
  • Functional MRI (fMRI)
  • Ictal SPECT
  • Interictal PET
  • Intracranial monitoring with depth electrodes and cortical electrode grids

Our clinical interventions include vagal nerve stimulators and deep brain stimulation, temporal lobectomies and extratemporal lesionectomies, and ketogenic and modified Atkins diets. The center actively participates in multi-center clinical trials of new medications and emerging therapies.

Introduction from the Director

Ohio State’s Comprehensive Epilepsy Center combines industry-leading research with world-class patient care. Our interdisciplinary approach allows our team to gain a more complete understanding of epilepsy through proven, promising, and pioneering testing and treatments. From advanced diagnostics and modified diets to complex surgical interventions unavailable elsewhere, our depth and breadth of experience and options offer the privilege to transform the lives of patients and their families.

Center Highlights

Exploring the effectiveness of medication is our first course of treatment. An epilepsy pharmacist is available to answer questions, provide support, and help with medication management. Our nutritionists and dietitians work to create meals plans for modified Atkins and ketogenic low-carb diets, which may be effective in reducing seizures.

The Ohio State Wexner Medical Center also offers advanced therapies proven extremely effective, even for persistent seizures.

  • Vagal nerve stimulators: Almost like a pacemaker for the brain, this sends mild electrical pulses to the vagas nerve in the neck to prevent seizures.
  • Deep brain stimulation: Electrodes are placed in targeted areas of the brain so mild electrical impulses may be used to reduce or stop seizures.
  • Temporal lobectomies: A surgeon removes areas of the brain where seizures start to reduce their severity or stop them altogether.
  • Extratemporal lesionectomies: Damaged areas of the brain that may result from tumors, scars from injury or infection, abnormal blood vessels, or hematomas—are removed to minimize or stop seizures.

If patients with epilepsy become pregnant, we partner with our Maternal Fetal Medicine experts in our High-Risk Pregnancy Clinic. We carefully prescribe medications and dosages to minimize risks and complications.

BrainGraphicEpilepsyRefer a patient

Ohio State’s Comprehensive Epilepsy Center is designated as a Level 4 epilepsy center by the National Association of Epilepsy Centers. Our center provides patients the highest quality care by a collaborative team of experts working under the banner of Ohio State’s Neurological Institute.

Learn more


Research and Clinical Trials

Our Team

Claire Speelman

Claire Speelman, PhD

  • Assistant Professor, Department of Neurology

Crystal Epley, MSN, APRN-CNP

  • Advanced Practice Provider - Epilepsy Division
Lucretia Long, APRN-CNP

Lucretia Long, APRN-CNP, FAES

  • Director, Advanced Practice Provider Operations

Advanced Practice Providers


Lucretia Long, MS, RN, CNP

Clinical Assistant Professor of Neurology; Epilepsy Nurse Practitioner

I received my BSN, MS and Nurse Practitioner Certification from Ohio State University. I have been on the OSU faculty since 1989. My areas of emphasis include epilepsy patient education and women's issues. I am well published in peer-reviewed nursing and medical journals, and I serve as a reviewer for Epilepsy and Behavior. I am a member of the local Epilepsy Foundation and the APP workgroup for the American Academy of Neurology. I am also national trainer for VNS (vagus nerve stimulation) therapy.

James McAuley, RPh, PhD

Professor of Pharmacy Practice and Neurology

In the Comprehensive Epilepsy Program, I have the opportunity to interact with patients and health care providers, teach and collaborate on clinical research projects. I received my PhD in Clinical Pharmaceutical Sciences from the University of Pittsburgh. I am the associate dean for Academic Affairs in the College of Pharmacy. My clinical interests include epilepsy, pharmacy, and patient outcomes. I also work closely with the Maternal-Fetal Medicine program, providing collaborative care to pregnant women with epilepsy.

Crystal Epley, APRN-CNP

Epilepsy Nurse Practitioner

 I earned my BSN from The Ohio State University and my MSN from Ohio University in 2016. I am a board-certified family nurse practitioner working in our comprehensive epilepsy outpatient clinic and in the Epilepsy Monitoring Unit (EMU). My clinical interests include epilepsy, drug-resistant or intractable epilepsy, epilepsy patient education, psychogenic non-epileptic spells (PNES) and neurostimulation. My academic interests include nursing education and quality improvement in the EMU.



James McAuley, RPh, PhD, FAPhA

Professor, Pharmacy Practice and Neurology

James McAuley is the associate dean for Academic Affairs in the College of Pharmacy. He received his bachelor's degree in Pharmacy and his PhD in Clinical Pharmaceutical Sciences, both from the University of Pittsburgh. Dr. McAuley’s clinical interests include epilepsy, women’s issues and pharmacotherapy.

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